OTTMUSG00000007655 Activators
Interferon alpha 15 precursor (interferon alpha 15) is a significant component of the type I interferon family, primarily involved in the body's antiviral response. As an extracellularly located protein, it plays a crucial role in the innate immune system, the body's first line of defense against viral infections. Interferon alpha 15 is known to bind to specific receptors on the surface of cells, triggering a cascade of signaling pathways that result in the upregulation of genes involved in antiviral activity. This upregulation is a key aspect of the body's ability to restrict viral replication and spread. The protein is also involved in modulating various immune responses, including the activation of natural killer cells and the enhancement of antigen presentation, which are vital in controlling viral infections.
The activation mechanisms of interferon alpha 15 involve complex interactions between various signaling molecules and pathways. Upon sensing viral infection or stimulation by specific molecules, such as those listed in the table, interferon alpha 15 is produced and released by cells, particularly immune cells. This release triggers a series of intracellular events, leading to the activation of various genes associated with the antiviral response. The chemicals listed are known to activate pathways that lead to the production of type I interferons, including interferon alpha 15. These activators work by mimicking viral components or stimulating immune receptors, such as toll-like receptors, which are critical in detecting viral components and initiating the immune response. The activation of these receptors leads to the activation of downstream signaling pathways, such as the NF-kB pathway, and the production of interferons. Some of the chemicals listed also work by modulating the immune response, enhancing the body's ability to produce and respond to interferon alpha 15. The overall activation of interferon alpha 15 is a coordinated event that involves both the recognition of viral components and the amplification of the immune response, ensuring a robust and efficient antiviral defense mechanism.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Polyinosinic-polycytidylic acid potassium salt | 31852-29-6 | sc-202767 | 5 mg | $198.00 | ||
Polyinosinic-polycytidylic acid, a synthetic analog of double-stranded RNA, can activate interferon alpha 15 by mimicking viral infection, triggering antiviral response pathways that involve this interferon. | ||||||
R-848 | 144875-48-9 | sc-203231 sc-203231A sc-203231B sc-203231C | 5 mg 25 mg 100 mg 500 mg | $102.00 $306.00 $510.00 $1559.00 | 12 | |
R-848, a toll-like receptor 7 and 8 agonist, can activate interferon alpha 15 by stimulating innate immune responses, leading to the production of type I interferons. | ||||||
Imiquimod | 99011-02-6 | sc-200385 sc-200385A | 100 mg 500 mg | $67.00 $284.00 | 6 | |
Imiquimod, another toll-like receptor 7 agonist, can activate interferon alpha 15 by inducing the innate immune response, which is crucial for interferon production and activation. | ||||||
Gardiquimod | 1020412-43-4 | sc-221663 sc-221663A sc-221663B sc-221663C sc-221663D sc-221663E sc-221663F | 25 mg 50 mg 100 mg 250 mg 5 g 10 g 25 g | $157.00 $282.00 $516.00 $1177.00 $20138.00 $32779.00 $70753.00 | 1 | |
Gardiquimod, targeting toll-like receptor 7, can activate interferon alpha 15 by initiating immune signaling pathways, resulting in the activation of type I interferon responses. | ||||||
Isoprinosine | 36703-88-5 | sc-279232 sc-279232A sc-279232B | 10 mg 100 mg 1 g | $120.00 $210.00 $270.00 | ||
Isoprinosine, an immunomodulator, can activate interferon alpha 15 by stimulating the immune system, particularly enhancing the production of type I interferons during immune responses. | ||||||
Amlexanox | 68302-57-8 | sc-217630 | 10 mg | $160.00 | 2 | |
Amlexanox, an inhibitor of TBK1 and IKK-ε, can indirectly activate interferon alpha 15 by modulating intracellular signaling pathways involved in innate immunity and interferon response. | ||||||
Emodin | 518-82-1 | sc-202601 sc-202601A sc-202601B | 50 mg 250 mg 15 g | $105.00 $214.00 $6255.00 | 2 | |
Emodin, a natural compound from plants, can activate interferon alpha 15 through its immunomodulatory effects, influencing pathways associated with type I interferon production. | ||||||
Bropirimine | 56741-95-8 | sc-362719 sc-362719A | 10 mg 50 mg | $52.00 $183.00 | ||
Bropirimine, a synthetic immunomodulator, can activate interferon alpha 15 by stimulating the immune system, specifically inducing pathways leading to the production of type I interferons. | ||||||
Loxoribine | 121288-39-9 | sc-203118 sc-203118A | 25 mg 100 mg | $124.00 $390.00 | 1 | |
Loxoribine, a guanosine analog, can activate interferon alpha 15 by targeting toll-like receptor 7, thereby inducing immune responses involving type I interferon activation. | ||||||