Date published: 2026-6-26

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OSTF1 Activators

OSTF1 activators are chemical compounds that can indirectly influence the activity and function of Osteoclast-stimulating factor 1 (OSTF1) by impacting various cellular pathways and processes. These compounds play pivotal roles in bone physiology and are involved in osteoclastogenesis and bone remodeling.

Calcitriol promotes calcium absorption, indirectly impacting OSTF1 by modulating calcium homeostasis, which is crucial for bone metabolism. Additionally, M-CSF (Macrophage Colony-Stimulating Factor), promotes osteoclastogenesis and osteoclast activity, indirectly impacting OSTF1 by stimulating the differentiation and function of osteoclasts. Strontium Ranelate enhances bone formation and reduces bone resorption, indirectly affecting OSTF1 by promoting a more favorable bone microenvironment. Alendronate inhibits bone resorption, indirectly influencing OSTF1 by reducing osteoclast activity. Estrogen maintains bone density, indirectly affecting OSTF1 by preserving bone health. Romosozumab inhibits sclerostin, indirectly activating OSTF1 by preventing the inhibition of osteoblast activity. Tacrolimus (FK-506) impacts osteoclast function through calcineurin-mediated pathways, indirectly affecting OSTF1 by modulating intracellular signaling. PGE2 (Prostaglandin E2) promotes osteoclast formation, indirectly impacting OSTF1 by regulating cellular responses involved in bone remodeling. Denosumab inhibits RANKL, indirectly affecting OSTF1 by blocking a key regulator of osteoclast differentiation and activity.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

1α,25-Dihydroxyvitamin D3

32222-06-3sc-202877B
sc-202877A
sc-202877C
sc-202877D
sc-202877
50 µg
1 mg
5 mg
10 mg
100 µg
$220.00
$645.00
$1000.00
$1500.00
$440.00
32
(2)

Promotes calcium absorption, indirectly impacting OSTF1.

GM-CSF

83869-56-1sc-280759
5 µg
$516.00
1
(0)

Promotes osteoclastogenesis and osteoclast activity, indirectly impacting OSTF1.

Strontium Ranelate

135459-87-9sc-208403
10 mg
$320.00
(0)

Enhances bone formation and reduces bone resorption, indirectly affecting OSTF1.

Alendronate acid

66376-36-1sc-337520
5 g
$135.00
2
(0)

Inhibit bone resorption, indirectly influencing OSTF1.

β-Estradiol

50-28-2sc-204431
sc-204431A
500 mg
5 g
$63.00
$182.00
8
(1)

Maintains bone density, indirectly affecting OSTF1.

FK-506

104987-11-3sc-24649
sc-24649A
5 mg
10 mg
$78.00
$151.00
9
(1)

Impact osteoclast function through calcineurin-mediated pathways, indirectly affecting OSTF1.

PGE2

363-24-6sc-201225
sc-201225C
sc-201225A
sc-201225B
1 mg
5 mg
10 mg
50 mg
$57.00
$159.00
$275.00
$678.00
37
(1)

Promotes osteoclast formation, indirectly impacting OSTF1.