OSAP Inhibitors
OSAP Inhibitors refer to a class of chemical compounds specifically designed to target and modulate the activity of the OSAP protein. OSAP, or oral cancer overexpressed protein, has been identified as a potential biomarker for these malignancies. It is a transmembrane protein, meaning it spans the cell's lipid bilayer, with its portions exposed both inside and outside the cell. Inhibitors of OSAP are developed to interact with this protein, potentially influencing its function, localization, or interactions with other cellular components. The mechanisms by which OSAP inhibitors exert their effects can vary, but their primary purpose is to serve as research tools for scientists studying the roles and functions of OSAP in cancer biology and oral cancer, in particular.
Structurally, OSAP inhibitors are designed to engage specific regions or binding sites on the OSAP protein. This interaction can disrupt the normal functioning of OSAP, potentially affecting its involvement in cellular processes or signaling pathways related to oral cancer development. The study of OSAP inhibitors and their interactions with the OSAP protein can contribute to a deeper understanding of the molecular mechanisms underlying oral cancer and may aid in the development of diagnostic tools in the future. Additionally, it can shed light on the broader field of cancer biology and the role of specific proteins in cancer initiation and progression, providing insights into the complex interplay of molecules in this disease.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rotenone | 83-79-4 | sc-203242 sc-203242A | 1 g 5 g | $89.00 $254.00 | 41 | |
Rotenone is a known inhibitor of mitochondrial complex I. By inhibiting mitochondrial function, it could potentially affect the expression or function of proteins associated with mitochondria, including MGARP. | ||||||
Antimycin A | 1397-94-0 | sc-202467 sc-202467A sc-202467B sc-202467C | 5 mg 10 mg 1 g 3 g | $54.00 $62.00 $1642.00 $4600.00 | 51 | |
An inhibitor of mitochondrial complex III. Disruption of the mitochondrial respiratory chain could indirectly affect MGARP expression or function. | ||||||
Oligomycin | 1404-19-9 | sc-203342 sc-203342C | 10 mg 1 g | $146.00 $12250.00 | 18 | |
This compound inhibits mitochondrial ATP synthase. Affecting ATP production can indirectly impact mitochondrial-associated proteins. | ||||||
Carbonyl Cyanide m-Chlorophenylhydrazone | 555-60-2 | sc-202984A sc-202984 sc-202984B | 100 mg 250 mg 500 mg | $75.00 $150.00 $235.00 | 8 | |
A protonophore and uncoupler of oxidative phosphorylation in mitochondria. It could potentially affect MGARP through mitochondrial disruption. | ||||||
Valinomycin | 2001-95-8 | sc-200991 | 25 mg | $163.00 | 3 | |
A potassium ionophore that disrupts the mitochondrial membrane potential. This disruption might indirectly affect MGARP expression. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
Acts by inhibiting glycolysis and can indirectly influence mitochondrial function and associated proteins. | ||||||
Mdivi-1 | 338967-87-6 | sc-215291 sc-215291B sc-215291A sc-215291C | 5 mg 10 mg 25 mg 50 mg | $66.00 $124.00 $246.00 $456.00 | 13 | |
An inhibitor of mitochondrial division, it affects mitochondrial morphology and could influence proteins like MGARP. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
An inhibitor of N-linked glycosylation, affecting protein processing in the ER, which could indirectly influence mitochondrial proteins. | ||||||
FCCP | 370-86-5 | sc-203578 sc-203578A | 10 mg 50 mg | $92.00 $348.00 | 46 | |
Another uncoupler of oxidative phosphorylation. It disrupts mitochondrial function, which might affect MGARP. | ||||||
Actinonin | 13434-13-4 | sc-201289 sc-201289B | 5 mg 10 mg | $160.00 $319.00 | 3 | |
Affects mitochondrial peptide deformylase, potentially influencing mitochondrial protein synthesis and function. | ||||||