Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Actinomycin D binds directly to DNA sequences and inhibits RNA polymerase, leading to a shutdown in transcriptional activity that would decrease the synthesis of OR8U8 mRNA. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
This histone deacetylase inhibitor promotes acetylation of histone proteins, thereby enhancing chromatin relaxation and decreasing transcriptional repression, potentially reducing OR8U8 expression. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
By inhibiting the enzyme DNA methyltransferase, 5-Azacytidine reduces DNA methylation levels, which can disrupt the normal silencing of gene expression, potentially decreasing OR8U8 transcription. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $55.00 | 6 | |
Mithramycin A binds selectively to GC-rich DNA sequences, blocking access of transcriptional machinery to these regions and leading to a reduction in transcription, including potentially of the OR8U8 gene. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $97.00 $328.00 $676.00 $1467.00 | 6 | |
Rifampicin can indirectly decrease transcription of eukaryotic genes by altering the function of nuclear receptors that control gene expression, potentially leading to reduced OR8U8 expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin decreases transcriptional activity by altering the function of specific transcription factors, which could lead to a reduction in OR8U8 mRNA levels. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol promotes deacetylation of histones, typically leading to tighter chromatin structure and a decrease in transcriptional activity of certain genes, including potentially OR8U8. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate inhibits histone deacetylases, which generally results in a more open chromatin structure and decreased transcriptional repression; however, it can lead to specific gene downregulation like OR8U8. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Vorinostat enhances histone acetylation, leading to decreased transcriptional repression overall, but can specifically downregulate the transcription of genes such as OR8U8. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid binds to retinoic acid receptors, altering the transcriptional activity of specific target genes, which can result in decreased expression of OR8U8. | ||||||