Olfr982 Activators
Olfr982, as a member of the olfactory receptor family, plays a crucial role in the sense of smell. These receptors, which are part of the G protein-coupled receptors (GPCRs) group, are primarily expressed in the olfactory epithelium and are responsible for detecting odorant molecules in the environment. The primary function of Olfr982 is to recognize specific volatile compounds, a process that is fundamental for olfaction. Upon binding an odorant, Olfr982 undergoes a conformational change that triggers a series of intracellular signaling events. These events lead to the translation of the chemical signal into a neural signal, which is then processed by the brain as a distinct scent. This ability to detect and respond to odorants is crucial for various survival-related behaviors, including locating food, detecting hazards, and social communication.
The activation mechanism of Olfr982 involves the specific interaction between the receptor and odorant molecules. The binding of an odorant to Olfr982 initiates a cascade of molecular events. Once activated, the receptor undergoes a structural change, which leads to the activation of a G protein on the inner surface of the cell membrane. The activated G protein stimulates adenylate cyclase, catalyzing the conversion of ATP to cyclic AMP (cAMP). The increase in cAMP levels triggers the activation of protein kinase A (PKA), which phosphorylates target proteins, including ion channels. This phosphorylation results in the opening of ion channels, leading to a change in the cell's membrane potential. The change in membrane potential generates a neural signal that is transmitted to the brain, where it is interpreted as a specific odor. The specificity of this process, from ligand-receptor interaction to neural signal generation, underscores the complexity and precision of the olfactory system. This system's ability to detect and differentiate a vast array of odorant molecules is fundamental to an organism's interaction with its environment, influencing survival, behavior, and physiological responses.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
2-Propanol | 67-63-0 | sc-391000C sc-391000 sc-391000B sc-391000A | 1 ml 25 ml 100 ml 500 ml | $33.00 $53.00 $63.00 $89.00 | 1 | |
2-Propanol binds to Olfr982, resulting in the activation of the receptor and initiation of its specific signaling pathway, leading to downstream cellular responses. | ||||||
Dipentene | 138-86-3 | sc-252747 | 4 L | $120.00 | ||
Dipentene interacts with Olfr982, activating the receptor through a conformational change which then propagates the signal through its specific signaling pathway. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $52.00 $115.00 | 2 | |
α-Pinene binds to and activates Olfr982, which leads to a series of reactions in the signaling pathway associated with this receptor, resulting in a cellular response. | ||||||
1,8-Cineole | 470-82-6 | sc-485261 | 25 ml | $44.00 | 2 | |
1,8-Cineole activates Olfr982 by binding to its ligand-binding domain, causing a change in the receptor's structure and initiating its signaling pathway. | ||||||
(±)-Menthol | 89-78-1 | sc-250299 sc-250299A | 100 g 250 g | $39.00 $68.00 | ||
Menthol activates Olfr982 through binding to the receptor, causing a conformational shift that initiates the signaling pathway of the receptor. | ||||||
(±)-beta-Citronellol | 106-22-9 | sc-294094 sc-294094A | 25 ml 500 ml | $32.00 $156.00 | ||
Citronellol binds to Olfr982, activating the receptor and leading to the initiation of its associated signaling mechanisms. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol activates Olfr982 by interacting with its ligand-binding domain, inducing a structural change that triggers the activation of the receptor's signaling pathway. | ||||||