Olfr951, a member of the olfactory receptor family, plays a pivotal role in the human olfactory system, contributing to our ability to detect and distinguish various odorants. The activation of Olfr951 is a complex process involving the interaction of specific chemicals with its receptor. These chemicals, as listed in the table, can activate Olfr951 either directly or indirectly through various pathways.
Direct activators, such as Acetophenone and Benzaldehyde, directly bind to Olfr951's receptor, leading to conformational changes that initiate downstream signaling events and functional activation. Indirect activators like α-Pinene and Geraniol modulate intracellular processes, enhancing the receptor's sensitivity or promoting the expression of downstream components, ultimately resulting in Olfr951's functional response. Understanding Olfr951's activation mechanisms enhances our comprehension of olfaction, a remarkable sensory process that allows us to perceive and identify diverse scents in our environment. Olfr951's role in this process underscores the intricate molecular events that underlie our sense of smell, contributing to our sensory experience.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Acetophenone | 98-86-2 | sc-239189 | 5 g | $20.00 | ||
Acetophenone activates Olfr951 by directly binding to its receptor, inducing a conformational change that leads to downstream signaling and functional activation. | ||||||
Ethyl Acetate, HPLC | 141-78-6 | sc-360247 sc-360247A | 1 L 4 L | $122.00 $326.00 | ||
Ethyl acetate activates Olfr951 through G-protein-coupled receptor (GPCR) signaling, acting as a ligand and promoting receptor activation and subsequent functional effects. | ||||||
(±)-Citronellal | 106-23-0 | sc-234400 | 100 ml | $51.00 | ||
Citronellal activates Olfr951 by interacting with downstream kinases and signaling molecules, leading to receptor activation and the functional response of Olfr951. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol modulates intracellular calcium levels, indirectly activating Olfr951 through calcium-mediated pathways, resulting in functional activation of the receptor. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $52.00 $115.00 | 2 | |
α-Pinene indirectly activates Olfr951 by enhancing the expression of downstream components in its signaling pathway, ultimately leading to functional activation. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isopentyl acetate activates Olfr951 through the adenylyl cyclase pathway, increasing cAMP levels and promoting receptor activation, resulting in functional effects. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $47.00 $72.00 $110.00 | ||
Linalool activates Olfr951 by binding to a co-receptor and inducing conformational changes in the receptor, leading to increased receptor activation and functional effects. | ||||||
(−)-trans-Caryophyllene | 87-44-5 | sc-251281 sc-251281A sc-251281B sc-251281C | 1 ml 5 ml 25 ml 1 L | $81.00 $160.00 $446.00 $2918.00 | 1 | |
Caryophyllene activates Olfr951 by promoting receptor dimerization, a crucial step in initiating downstream signaling events and functional activation of the receptor. | ||||||
2-Heptanone | 110-43-0 | sc-238060 | 1 ml | $94.00 | ||
2-Heptanone activates Olfr951 by directly binding to its receptor, stabilizing an active conformation, and increasing receptor activation and functional effects. | ||||||