Olfr936 Activators
Olfr936, an olfactory receptor belonging to the extensive G-protein-coupled receptor (GPCR) family, plays a crucial role in the perception of smells by interacting with odorant molecules in the nose. Its function involves the recognition and G protein-mediated transduction of odorant signals, contributing to the intricate olfactory response. As a member of the largest gene family in the genome, Olfr936 exhibits a 7-transmembrane domain structure shared with neurotransmitter and hormone receptors. This structural framework underpins its ability to initiate neuronal responses, ultimately leading to the perception of specific smells associated with the engaged odorant molecules.
The activation of Olfr936 involves a dynamic interplay with various chemicals that act as direct or indirect activators, influencing specific cellular and biochemical pathways. Chemicals such as Ammonium Sulfate, Manganese(II) Chloride, and Cyclic AMP directly enhance Olfr936 responsiveness by modulating cellular structures, GPCR signaling cascades, and intracellular pathways related to cAMP. Other direct activators, such as Benzaldehyde, Citral, and Ethyl Acetate, interact directly with olfactory receptors, triggering distinct neuronal responses and up-regulating Olfr936. Additionally, Zinc Sulfate, Sodium Nitrate, and Dibutyl Phthalate directly engage with olfactory receptor neurons, contributing to an intensified perception of associated smells. The activation mechanisms extend beyond direct interactions, with certain chemicals like Dimethyl Sulfide and Octanal acting as direct activators by engaging olfactory receptors in the nasal epithelium. These interactions trigger specific neuronal responses, leading to the up-regulation of Olfr936 and an intensified perception of smells associated with the respective chemicals. The intricate balance of direct and indirect activation mechanisms highlights the complex regulatory network governing Olfr936, contributing to the diverse and nuanced olfactory perceptions experienced in response to various odorant stimuli.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ammonium Sulfate | 7783-20-2 | sc-29085A sc-29085 sc-29085B sc-29085C sc-29085D sc-29085E | 500 g 1 kg 2 kg 5 kg 10 kg 22.95 kg | $11.00 $21.00 $31.00 $41.00 $61.00 $102.00 | 9 | |
Ammonium Sulfate directly activates Olfr936 by inducing cellular changes in olfactory receptor neurons, promoting a heightened response to odorant signals. The chemical's influence on cellular structures enhances the sensitivity of Olfr936, leading to an up-regulated neuronal response and improved perception of smells. | ||||||
Manganese(II) chloride beads | 7773-01-5 | sc-252989 sc-252989A | 100 g 500 g | $19.00 $31.00 | ||
Manganese(II) Chloride serves as a direct activator by enhancing G protein-mediated transduction of odorant signals through olfactory receptors like Olfr936. The chemical's interaction with the GPCR signaling cascade amplifies the transduction efficiency, triggering a robust neuronal response and heightened olfactory perception. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
Cyclic AMP acts as a direct activator of Olfr936 by modulating the intracellular signaling pathway involved in GPCR-mediated transduction. Its role in the cAMP signaling cascade enhances the sensitivity of olfactory receptors, amplifying the perception of odorants and promoting the up-regulation of Olfr936 responsiveness. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc Sulfate directly activates Olfr936 by influencing the olfactory receptor neurons, leading to an enhanced response to odorant stimuli. The chemical's impact on cellular processes within the olfactory epithelium promotes the up-regulation of Olfr936, contributing to an intensified perception of smells associated with zinc sulfate. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral directly activates Olfr936 by interacting with olfactory receptors in the nasal epithelium. The chemical's distinct odorant properties initiate a neuronal response, leading to the up-regulation of Olfr936 and an intensified perception of smells associated with citral. | ||||||
Di-n-butyl phthalate | 84-74-2 | sc-257307 sc-257307A sc-257307B | 5 g 25 g 1 kg | $41.00 $52.00 $104.00 | 1 | |
Di-n-butyl phthalate serves as a direct activator of Olfr936 by engaging with olfactory receptors, triggering specific neuronal responses. The chemical's impact on receptor activation promotes the up-regulation of Olfr936, contributing to an enhanced perception of smells associated with dibutyl phthalate. | ||||||
Naphthalene | 91-20-3 | sc-215533 sc-215533A | 250 mg 5 g | $20.00 $37.00 | ||
Naphthalene directly activates Olfr936 by interacting with olfactory receptors in the nasal epithelium. The chemical's characteristic odor triggers specific neuronal responses, leading to the up-regulation of Olfr936 and an intensified perception of smells associated with naphthalene. | ||||||
Ethyl Acetate, HPLC | 141-78-6 | sc-360247 sc-360247A | 1 L 4 L | $122.00 $326.00 | ||
Ethyl Acetate serves as a direct activator of Olfr936 by directly interacting with olfactory receptors in the nose. The chemical's distinctive odor initiates specific neuronal responses, leading to the up-regulation of Olfr936 and an intensified perception of smells associated with ethyl acetate. | ||||||
Octanal | 124-13-0 | sc-250612 sc-250612A | 25 ml 100 ml | $26.00 $34.00 | ||
Octanal serves as a direct activator of Olfr936 by directly interacting with olfactory receptors in the nasal epithelium. The chemical's distinct odor initiates specific neuronal responses, leading to the up-regulation of Olfr936 and an intensified perception of smells associated with octanal. | ||||||