Olfr694 Activators
Olfr695 is a specific target protein that plays a pivotal role in the intricate field of olfaction. As a member of the olfactory receptor (OR) family, Olfr695 is primarily expressed in sensory neurons of the olfactory epithelium. Its main function lies in detecting and transducing odorant signals from the environment into neural impulses that can be interpreted by the brain. Specifically, Olfr695 belongs to the G protein-coupled receptor (GPCR) superfamily, which is renowned for its vital role in initiating intracellular signaling cascades in response to extracellular ligand binding. The general mechanisms of activation for Olfr695 are intricately linked to its nature as a GPCR. When an odorant molecule, a chemical compound with a specific structure, comes into contact with the olfactory epithelium, it can interact with Olfr695 through a process known as odorant-receptor binding. This interaction triggers a cascade of events: upon binding, Olfr695 undergoes conformational changes, leading to the activation of associated G proteins. These G proteins, in turn, activate the enzyme adenylyl cyclase, leading to the conversion of adenosine triphosphate (ATP) into cyclic adenosine monophosphate (cAMP). Elevated cAMP levels then activate protein kinase A (PKA), which phosphorylates various downstream effector proteins, ultimately culminating in the generation of action potentials that are transmitted to the brain for odor perception.
Furthermore, Olfr695 activation is highly sensitive and specific, as different odorant molecules exhibit distinct chemical structures, allowing for a diverse range of odor discrimination. This specificity is critical for our ability to distinguish between various odors in our environment. It's important to note that while the general mechanisms of Olfr695 activation are well-established, the specific odorants that activate this receptor can vary widely and are not mentioned in this context. Understanding the function and activation of Olfr695 is essential for unraveling the complexities of olfaction, an intricate sensory process that continues to be a subject of intense scientific investigation and discovery in the realm of chemical biology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $52.00 $115.00 | 2 | |
Alpha-Pinene, a monoterpene, can interact with olfactory receptor protein Olfr694. By binding to the ligand-binding site of Olfr694, Alpha-Pinene directly activates the receptor, triggering a G-protein coupled receptor (GPCR) cascade. This activation leads to intracellular signaling alterations, resulting in specific cellular responses characteristic of Olfr694 activation. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol, a phenylpropene, activates Olfr694 by binding to its active site. This interaction stimulates the GPCR pathway associated with Olfr694. Upon activation, Eugenol initiates a signal transduction cascade that amplifies the receptor's response, demonstrating a direct and functional activation of Olfr694, leading to the receptor's specific physiological response. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral, a monoterpenoid, binds to and activates Olfr694. It functions as a direct activator by interacting with the receptor's ligand-binding domain, facilitating a conformational change that activates the GPCR pathway. This leads to downstream signaling events unique to Olfr694 activation, thereby influencing cellular processes that are regulated by this specific olfactory receptor. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
Limonene, a cyclic monoterpene, serves as a direct activator of Olfr694. By binding to Olfr694, Limonene triggers a series of intracellular reactions via the GPCR mechanism. This binding and subsequent receptor activation lead to a cascade of cellular events specifically tailored to Olfr694's role in olfactory signaling, thereby effectively activating the receptor's intended biological function. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $47.00 $72.00 $110.00 | ||
Linalool, a terpene alcohol, activates Olfr694 by directly binding to its active site. This interaction induces the GPCR-mediated signaling pathway associated with Olfr694. The activation process involves the receptor undergoing conformational changes, leading to the initiation of intracellular signaling cascades that are a direct consequence of Olfr694 activation, underscoring its functional role in olfactory perception. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol, a monoterpenoid alcohol, directly activates Olfr694. It binds to the receptor's ligand-binding region, initiating the GPCR signaling pathway. The interaction of Geraniol with Olfr694 results in receptor activation, which then triggers a specific series of intracellular events. These events are indicative of Olfr694's direct activation, leading to its unique cellular response. | ||||||
Isoeugenol | 97-54-1 | sc-250186 sc-250186A | 5 g 100 g | $63.00 $53.00 | ||
Isoeugenol, a phenylpropene derivative, binds and activates Olfr694. The chemical interacts with the receptor's active site, triggering the GPCR pathway specific to Olfr694. This activation elicits a sequence of intracellular signaling events, characteristic of Olfr694's function. Isoeugenol's ability to directly activate Olfr694 highlights its role in modulating specific olfactory responses. | ||||||
cis-3,7-Dimethyl-2,6-octadien-1-ol | 106-25-2 | sc-234382 | 5 ml | $51.00 | ||
cis-3,7-Dimethyl-2,6-octadien-1-ol, a monoterpenoid, acts as a direct activator of Olfr694. It interacts with the receptor's binding site, initiating the GPCR signaling cascade associated with Olfr694. This direct activation leads to a series of receptor-specific cellular responses, demonstrating Nerol's role in directly influencing Olfr694's physiological function in olfactory signaling processes. | ||||||
(±)-beta-Citronellol | 106-22-9 | sc-294094 sc-294094A | 25 ml 500 ml | $32.00 $156.00 | ||
Citronellol, a monoterpenoid alcohol, activates Olfr694 by binding to its ligand-binding domain. This interaction triggers the GPCR mechanism inherent to Olfr694, leading to a specific intracellular signaling pathway activation. Citronellol's direct activation of Olfr694 illustrates its functional role in the receptor's signaling processes, directly influencing cellular responses mediated by Olfr694. | ||||||
(+)-Carvone | 2244-16-8 | sc-239480 sc-239480A | 5 ml 25 ml | $33.00 $84.00 | 2 | |
Carvone, a monoterpenoid ketone, activates Olfr694 through direct binding to its active site. This interaction stimulates the receptor's GPCR pathway | ||||||