Olfr667 Activators
Olfr667 is an olfactory receptor, a critical component of the G protein-coupled receptor (GPCR) family, essential for the sense of smell. This receptor type specializes in detecting odorant molecules and transforming these chemical signals into neural signals that are perceived as different smells by the brain. Olfr667's role in distinguishing a variety of odorants is integral to numerous behavioral and physiological responses. The activation of Olfr667 follows a specific molecular process. When an odorant molecule binds to Olfr667, it triggers a conformational change in the receptor, a pivotal event in the activation sequence. This structural alteration facilitates the interaction of Olfr667 with G proteins inside the cell membrane. The subsequent activation of these G proteins leads to their dissociation into subunits, which interact with downstream cellular components, generating secondary messengers. These messengers propagate the signal within the cell, resulting in a response that is typically manifested as an electrical impulse in olfactory sensory neurons. This impulse is then relayed to the brain and interpreted as a distinct smell.
The chemicals listed in the table have been identified as potential activators of Olfr667 based on their structural properties and known interactions with similar receptors. These interactions are believed to bind effectively to Olfr667, inducing the necessary conformational changes for GPCR signaling. Understanding how these chemicals activate Olfr667 deepens our knowledge of olfactory signaling mechanisms. This insight is valuable for advancing scientific research in sensory biology and has practical applications in developing artificial scent technologies, as well as novel approaches for modulating olfactory functions in various industries.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $31.00 $61.00 $214.00 | 2 | |
Eugenol activates Olfr667 by binding to its ligand-binding domain, inducing a conformational change, and triggering the GPCR signaling pathway for olfactory signal transduction. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $43.00 $122.00 | 1 | |
Vanillin activates Olfr667 through direct interaction with the ligand-binding site, causing a structural change that leads to GPCR-mediated signal transduction related to olfaction. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $105.00 $221.00 | ||
Isopentyl acetate activates Olfr667 by binding to the receptor, mimicking natural ligands, and initiating the GPCR cascade for olfactory signal propagation. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $82.00 $126.00 | 3 | |
Limonene activates Olfr667 by binding to its ligand-binding domain, leading to a structural change in the receptor and activation of the GPCR pathway for olfactory perception. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $46.00 $69.00 | ||
Methyl salicylate activates Olfr667 by interacting with the ligand-binding domain, causing a conformational change and initiating the GPCR pathway for olfactory signal transduction. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $44.00 $117.00 | ||
Geraniol activates Olfr667 by binding to specific receptor sites, leading to a conformational change and the activation of G protein-mediated signal transduction for smell perception. | ||||||
trans-Anethole | 4180-23-8 | sc-253727 | 1 ml | $27.00 | 1 | |
Anethole activates Olfr667 by interacting with its ligand-binding domain, inducing a structural change and activating the GPCR signaling pathway for olfactory signal propagation. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate activates Olfr667 by binding to the ligand-binding domain, causing a structural change and activating the GPCR pathway for olfactory signal transmission. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $102.00 $224.00 | ||
Cinnamic Aldehyde activates Olfr667 by direct interaction with the receptor, binding to the ligand-binding domain, and inducing a conformational change that triggers G protein-mediated signaling. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $51.00 $113.00 | 2 | |
Alpha-Pinene activates Olfr667 by binding to its ligand-binding domain, causing a structural change in the receptor, and initiating the GPCR-mediated signaling pathway for olfactory signal transduction. | ||||||