Date published: 2025-12-7

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Nitric Oxide Donors

Santa Cruz Biotechnology now offers a broad range of nitric oxide donors for use in various applications. Nitric oxide (NO) donors are chemical compounds that release nitric oxide, a vital signaling molecule involved in numerous physiological and pathological processes. These donors are crucial tools in scientific research for studying the roles of nitric oxide in vascular biology, neurotransmission, immune response, and cellular signaling. Researchers use nitric oxide donors to investigate the mechanisms by which NO regulates blood flow, modulates neurotransmitter release, and mediates immune defense mechanisms. These compounds are also employed in exploring the pathophysiology of conditions such as hypertension, neurodegenerative diseases, and inflammatory disorders. By providing a controlled and sustained release of nitric oxide, NO donors enable the detailed study of its biological effects and the elucidation of NO-dependent signaling pathways. Furthermore, nitric oxide donors are instrumental in developing experimental models to understand NO's role in various cellular processes and to identify new fundemental targets. By offering a comprehensive selection of high-quality nitric oxide donors, Santa Cruz Biotechnology supports advanced research in physiology and cell biology. These products empower scientists to achieve precise and reproducible results, driving advancements in our understanding of nitric oxide biology and its applications in health and disease. View detailed information on our available nitric oxide donors by clicking on the product name.

Items 31 to 40 of 56 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Glyco-SNAP-1

188849-81-2sc-221680
sc-221680A
5 mg
25 mg
$265.00
$663.00
1
(1)

Glyco-SNAP-1 functions as a nitric oxide donor, characterized by its selective release mechanism that is influenced by pH and specific biological environments. This compound exhibits unique interactions with thiol groups, facilitating the formation of S-nitrosothiols, which can influence signaling pathways. Its reaction kinetics are notable for their rapid onset, allowing for precise modulation of nitric oxide levels. Glyco-SNAP-1's solubility in various solvents enhances its versatility in diverse chemical contexts.

β-Gal NONOate

357192-78-0sc-202861
sc-202861A
1 mg
5 mg
$36.00
$136.00
(0)

β-Gal NONOate serves as a nitric oxide donor, distinguished by its ability to release nitric oxide in a controlled manner through hydrolysis. This compound engages in specific interactions with biological membranes, promoting localized effects. Its reaction kinetics are characterized by a gradual release profile, allowing for sustained nitric oxide production. Additionally, β-Gal NONOate's stability in aqueous environments enhances its utility in various experimental setups, making it a versatile tool for studying nitric oxide dynamics.

4-(p-methoxyphenyl)-1,3,2-Oxathiazolylium-5-olate

sc-223600
sc-223600A
5 mg
10 mg
$50.00
$72.00
(0)

4-(p-methoxyphenyl)-1,3,2-Oxathiazolylium-5-olate acts as a nitric oxide donor, notable for its unique electron-rich structure that facilitates rapid NO release upon activation. This compound exhibits distinct molecular interactions with reactive species, enhancing its reactivity. Its reaction kinetics reveal a swift initiation phase, followed by a sustained release, allowing for precise modulation of nitric oxide levels. The compound's solubility in polar solvents further supports its versatility in diverse chemical environments.

Molsidomine

25717-80-0sc-200337
sc-200337A
50 mg
250 mg
$20.00
$32.00
(0)

Molsidomine serves as a nitric oxide donor characterized by its unique heterocyclic structure, which promotes efficient NO liberation through a specific enzymatic pathway. The compound's reactivity is influenced by its ability to form stable intermediates, leading to controlled release kinetics. Its interactions with biological membranes enhance permeability, facilitating the diffusion of nitric oxide. Additionally, Molsidomine's solubility in various solvents allows for adaptability in different chemical contexts.

Sulfo-NONOate disodium salt

61142-90-3sc-202348
sc-202348A
10 mg
25 mg
$32.00
$79.00
(0)

Sulfo-NONOate disodium salt is a potent nitric oxide donor distinguished by its sulfonate group, which enhances solubility and stability in aqueous environments. Its unique structure facilitates the release of nitric oxide through hydrolysis, promoting rapid reaction kinetics. The compound's ability to interact with metal ions can influence its reactivity, while its ionic nature allows for effective dispersion in biological systems, enhancing its potential for localized effects.

10-Nitrooleate

88127-53-1sc-204608
sc-204608A
50 µg
100 µg
$30.00
$43.00
(0)

10-Nitrooleate serves as a distinctive nitric oxide donor, characterized by its nitro group that modulates electron density, influencing its reactivity. This compound exhibits unique interaction dynamics with cellular membranes, promoting localized nitric oxide release. Its hydrophobic properties facilitate membrane penetration, while the presence of the nitro group alters reaction pathways, enabling selective activation of signaling cascades. The compound's stability under physiological conditions further enhances its utility in various biochemical contexts.

DD1

187585-11-1sc-221531
sc-221531A
10 mg
50 mg
$286.00
$1020.00
(0)

DD1 is a specialized nitric oxide donor that features a unique structural arrangement, allowing for rapid release of nitric oxide through specific enzymatic pathways. Its distinctive electron-withdrawing groups enhance the compound's reactivity, facilitating interactions with various biological targets. The compound's ability to form stable intermediates contributes to its controlled release profile, while its solubility characteristics enable effective diffusion across lipid membranes, promoting localized effects in cellular environments.

4-chloro-4-phenyl-1,3,2-Oxathiozolylium-5-olate

sc-223631
sc-223631A
5 mg
10 mg
$32.00
$62.00
(0)

4-chloro-4-phenyl-1,3,2-Oxathiozolylium-5-olate is a novel nitric oxide donor characterized by its unique oxathiazole ring structure, which promotes efficient NO release via redox reactions. The presence of the chloro and phenyl substituents enhances its electron density, facilitating rapid interactions with reactive species. This compound exhibits remarkable stability under physiological conditions, allowing for sustained nitric oxide generation, which is crucial for modulating various biochemical pathways.

4-phenyl-1,3,2-Oxathiazolylium-5-olate

sc-223664
sc-223664A
5 mg
10 mg
$32.00
$62.00
(0)

4-phenyl-1,3,2-Oxathiazolylium-5-olate serves as an innovative nitric oxide donor, distinguished by its unique oxathiazole framework that enables selective electron transfer processes. The compound's structural features promote a favorable environment for the generation of reactive nitrogen species, enhancing its reactivity. Its kinetic profile indicates a controlled release mechanism, allowing for precise modulation of nitric oxide levels, which can influence various biochemical interactions and signaling pathways.

4-trifluoro-4-phenyl-1,3,2-Oxathiazolylium-5-olate

sc-223666
sc-223666A
5 mg
10 mg
$32.00
$62.00
(0)

4-trifluoro-4-phenyl-1,3,2-Oxathiazolylium-5-olate is a distinctive nitric oxide donor characterized by its trifluoromethyl and phenyl substituents, which enhance its electron-withdrawing properties. This compound exhibits unique reactivity through its oxathiazole ring, facilitating rapid formation of nitric oxide under specific conditions. Its reaction kinetics reveal a tunable release profile, allowing for targeted modulation of nitric oxide, impacting various molecular interactions and pathways.