NDUFAF7 Activators
Chemical activators of N6-furfuryladenine can play a significant role in enhancing the functional activity of NDUFAF7, a protein integral to the assembly of mitochondrial Complex I. N6-furfuryladenine is known to activate adenine nucleotide translocator (ANT), which interacts with NDUFAF7 during the assembly process of Complex I, leading to an increase in ATP synthesis. This activation is further supported by the presence of Spermidine, which enhances autophagy, subsequently improving the turnover and assembly of mitochondrial complexes. The improved assembly of these complexes augments the activity of NDUFAF7. Coenzyme Q10, by participating in the electron transport chain, enhances electron flow, facilitating the assembly and activity of Complex I and indirectly supporting NDUFAF7's role. Cardiolipin, essential to the inner mitochondrial membrane, aids in the optimal functioning of Complex I, promoting the proper assembly and function of mitochondrial complexes, thus enhancing NDUFAF7's activity.
Additionally, Nicotinamide adenine dinucleotide (NADH) as a Complex I substrate, enhances the complex's activity, leading to increased activity of NDUFAF7. L-carnitine assists in the transport of fatty acids into mitochondria for β-oxidation, increasing the production of NADH and FADH2, which in turn enhances Complex I activity and NDUFAF7's functional activity. Mitoquinone mesylate, a targeted antioxidant, maintains the integrity of mitochondrial complexes and supports NDUFAF7's role in Complex I assembly. Copper (II) sulfate ensures the proper function of the electron transport chain, indirectly promoting NDUFAF7 activity. Alpha-lipoic acid serves as a mitochondrial cofactor and antioxidant, improving function and indirectly enhancing NDUFAF7 activity. Furthermore, Retinoic acid influences mitochondrial biogenesis and function, increasing NDUFAF7 activity. Leucine stimulates the mTOR pathway, leading to mitochondrial biogenesis and function, enhancing NDUFAF7 activity. Pyrroloquinoline quinone (PQQ) influences mitochondrial biogenesis and function, further supporting the activity of NDUFAF7.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Kinetin | 525-79-1 | sc-207780 sc-207780A | 1 g 5 g | $38.00 $48.00 | ||
Activates adenine nucleotide translocator (ANT) which is known to interact with NDUFAF7 during the assembly of Complex I in mitochondria, leading to an increase in ATP synthesis and subsequent activation of NDUFAF7 as a part of the complex. | ||||||
Spermidine | 124-20-9 | sc-215900 sc-215900B sc-215900A | 1 g 25 g 5 g | $57.00 $607.00 $176.00 | ||
Enhances autophagy which can increase the turnover and assembly of mitochondrial complexes, thereby potentially increasing the activity of NDUFAF7 in the context of its role in the assembly and maintenance of Complex I function. | ||||||
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $71.00 $184.00 | 1 | |
Directly involved in the mitochondrial electron transport chain, where NDUFAF7 functions. By enhancing electron flow, Coenzyme Q10 can increase the assembly and activity of Complex I, indirectly supporting the activity of NDUFAF7. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $57.00 $191.00 $302.00 $450.00 $1800.00 $3570.00 $10710.00 | 4 | |
As a substrate for Complex I, NADH can enhance the activity of the complex, potentially leading to increased functional activity of NDUFAF7, which is involved in the assembly and stabilization of Complex I. | ||||||
L-Carnitine | 541-15-1 | sc-205727 sc-205727A sc-205727B sc-205727C | 1 g 5 g 100 g 250 g | $23.00 $34.00 $79.00 $179.00 | 3 | |
Facilitates the transport of fatty acids into mitochondria for β-oxidation, which can increase the production of NADH and FADH2, thereby enhancing the activity of Complex I and potentially the functional activity of NDUFAF7. | ||||||
Mito-Q | 444890-41-9 | sc-507441 | 5 mg | $290.00 | ||
As a mitochondria-targeted antioxidant, it can maintain the integrity of mitochondrial complexes by preventing oxidative damage, supporting the functional activity of NDUFAF7 in the assembly of Complex I. | ||||||
Copper(II) sulfate | 7758-98-7 | sc-211133 sc-211133A sc-211133B | 100 g 500 g 1 kg | $46.00 $122.00 $189.00 | 3 | |
Copper is a cofactor for cytochrome c oxidase and its presence is crucial for the proper function of the electron transport chain. Enhanced electron transport chain function can indirectly activate NDUFAF7 by promoting Complex I activity. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $69.00 $122.00 $212.00 $380.00 $716.00 | 3 | |
Acts as a mitochondrial cofactor and antioxidant, potentially improving mitochondrial function and indirectly enhancing the activity of NDUFAF7 by promoting the assembly and stability of Complex I. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
A signaling molecule which can influence mitochondrial biogenesis and function, potentially increasing the activity of NDUFAF7 through enhanced Complex I assembly and function. | ||||||
L-Leucine | 61-90-5 | sc-364173 sc-364173A | 25 g 100 g | $21.00 $62.00 | ||
An amino acid that can stimulate the mammalian target of rapamycin (mTOR) pathway, leading to increased mitochondrial biogenesis and function, which could enhance the activity of NDUFAF7 by promoting Complex I activity. | ||||||