Date published: 2026-1-9

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Na+ CP type XIα Activators

Na+ CP type XIα Activators comprise a diverse group of chemical compounds that can enhance the functional activity of Na+ CP type XIα through various specific signaling pathways. For instance, Ouabain and Progesterone inhibit the Na+/K+ ATPase pump, thereby increasing intracellular sodium levels. Given Na+ CP type XIα's role in sodium transport, its activity can be enhanced by these compounds. Similarly, Veratridine, a sodium channel activator, prolongs the opening of sodium channels and increases sodium influx, which can lead to the activation of Na+ CP type XIα.

On the other hand, compounds such as Anandamide and Capsaicin activate the TRPV1 channel, leading to increased sodium influx, which can activate Na+ CP type XIα. Pregnenolone sulfate potentiates the activity of certain sodium channels, thereby increasing sodium influx and activating Na+ CP type XIα. Similarly, Loperamide, an opioid receptor agonist, inhibits certain types of calcium-activated potassium channels, increasing intracellular sodium levels, which can enhance the functional activity of Na+ CP type XIα. Moreover, Conotoxin, Batrachotoxin, Saxitoxin, Tetrodotoxin, and Lidocaine influence sodium channels in various ways, like inhibition or blockade, leading to an increase in intracellular sodium levels, which can enhance the functional activity of Na+ CP type XIα.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Ouabain-d3 (Major)

sc-478417
1 mg
$516.00
(0)

Ouabain is a potent inhibitor of the Na+/K+ ATPase pump. By inhibiting this pump, it increases intracellular sodium levels, which in turn can lead to the activation of the Na+ CP type XIα, given its role in sodium transport.

Veratridine

71-62-5sc-201075B
sc-201075
sc-201075C
sc-201075A
5 mg
10 mg
25 mg
50 mg
$82.00
$104.00
$201.00
$379.00
3
(1)

Veratridine is a sodium channel activator. It prolongs the opening of sodium channels, increasing sodium influx. This increased sodium concentration can enhance the functional activity of Na+ CP type XIα, given its role in sodium transport.

Capsaicin

404-86-4sc-3577
sc-3577C
sc-3577D
sc-3577A
50 mg
250 mg
500 mg
1 g
$96.00
$160.00
$240.00
$405.00
26
(1)

Capsaicin is a well-known activator of the TRPV1 channel. By activating this channel, it can increase sodium influx, which can lead to the activation of Na+ CP type XIα.

Progesterone

57-83-0sc-296138A
sc-296138
sc-296138B
1 g
5 g
50 g
$20.00
$52.00
$298.00
3
(1)

Progesterone has been shown to inhibit the Na+/K+ ATPase pump. This inhibition can increase intracellular sodium levels, which can enhance the functional activity of Na+ CP type XIα.

Pregnenolone

145-13-1sc-204860
sc-204860A
sc-204860B
sc-204860C
5 g
25 g
100 g
500 g
$87.00
$148.00
$347.00
$1122.00
(1)

Pregnenolone sulfate is a neurosteroid that can potentiate the activity of certain sodium channels. This potentiation can increase sodium influx, which can lead to the activation of Na+ CP type XIα.

Lidocaine

137-58-6sc-204056
sc-204056A
50 mg
1 g
$51.00
$131.00
(0)

Lidocaine is a local anesthetic that blocks voltage-gated sodium channels, leading to an increase in intracellular sodium levels. This can enhance the functional activity of Na+ CP type XIα.