MUP Activators
MUP activators represent a diverse group of chemicals that enhance its functional activity through specific signaling pathways and biological processes. Retinoic Acid and 9-cis-Retinoic Acid activate the retinoic acid receptor (RAR) pathway, enhancing MUP function by influencing its interactions with signaling components, ultimately impacting MUP-mediated processes associated with retinoic acid signaling. GW501516 (Cardarine), Rosiglitazone, and Bezafibrate activate peroxisome proliferator-activated receptors (PPARs) associated with MUP. They enhance MUP function by modulating its interactions with signaling components, leading to altered cellular responses to lipid metabolism and PPAR signaling. AICAR, Metformin, and Leptin activate AMP-activated protein kinase (AMPK) and JAK-STAT pathways, respectively. These activators influence MUP by altering energy-sensing pathways, impacting responses to metabolic stress and energy homeostasis, ultimately influencing MUP-mediated processes.
Thyroid Hormone (T3) activates thyroid hormone receptors (TR), enhancing MUP function by modulating its interactions with signaling components, impacting cellular responses to thyroid hormone signaling. Dihydrotestosterone (DHT) activates androgen receptors (AR), influencing MUP by altering interactions with signaling components involved in androgen signaling. Fibrates, exemplified by Clofibrate, activate PPARα, enhancing MUP function through altered interactions with signaling components, ultimately impacting MUP-mediated processes related to lipid metabolism and PPARα signaling. These activators collectively provide insights into potential regulatory mechanisms within the cellular processes associated with MUP.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid activates the retinoic acid receptor (RAR) signaling pathway. MUP is associated with retinoic acid signaling. Retinoic Acid-induced RAR activation enhances MUP function by influencing its interactions with signaling components, leading to altered cellular responses to retinoic acid signaling and impacting MUP-mediated processes. | ||||||
GW501516 | 317318-70-0 | sc-202642 sc-202642A | 1 mg 5 mg | $82.00 $179.00 | 28 | |
GW501516 is a selective agonist of peroxisome proliferator-activated receptor delta (PPARδ). MUP is implicated in PPARδ-mediated signaling pathways. GW501516-induced PPARδ activation enhances MUP function by influencing its interactions with signaling components, leading to altered cellular responses to lipid metabolism and PPARδ signaling, ultimately impacting MUP-mediated processes. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $120.00 $326.00 $634.00 $947.00 $1259.00 | 38 | |
Rosiglitazone is a selective agonist of peroxisome proliferator-activated receptor gamma (PPARγ). MUP is associated with PPARγ-mediated signaling pathways. Rosiglitazone-induced PPARγ activation enhances MUP function by influencing its interactions with signaling components, leading to altered cellular responses to lipid metabolism and PPARγ signaling, ultimately impacting MUP-mediated processes. | ||||||
9-cis-Retinoic acid | 5300-03-8 | sc-205589 sc-205589B sc-205589C sc-205589D sc-205589A | 1 mg 25 mg 250 mg 500 mg 5 mg | $71.00 $424.00 $3121.00 $5722.00 $148.00 | 10 | |
9-cis-Retinoic Acid activates the retinoic acid receptor (RAR) signaling pathway. MUP is associated with retinoic acid signaling. 9-cis-Retinoic Acid-induced RAR activation enhances MUP function by influencing its interactions with signaling components, leading to altered cellular responses to retinoic acid signaling and impacting MUP-mediated processes. | ||||||
Bezafibrate | 41859-67-0 | sc-204650B sc-204650 sc-204650A sc-204650C | 500 mg 1 g 5 g 10 g | $31.00 $46.00 $122.00 $204.00 | 5 | |
Bezafibrate activates peroxisome proliferator-activated receptor alpha (PPARα), a transcription factor involved in lipid metabolism. MUP is associated with PPARα-mediated signaling pathways. Bezafibrate-induced PPARα activation enhances MUP function by influencing its interactions with signaling components, leading to altered cellular responses to lipid metabolism and PPARα signaling, ultimately impacting MUP-mediated processes. | ||||||
WY 14643 | 50892-23-4 | sc-203314 | 50 mg | $136.00 | 7 | |
WY-14643 is a selective agonist of peroxisome proliferator-activated receptor alpha (PPARα). MUP is associated with PPARα-mediated signaling pathways. WY-14643-induced PPARα activation enhances MUP function by influencing its interactions with signaling components, leading to altered cellular responses to lipid metabolism and PPARα signaling, ultimately impacting MUP-mediated processes. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $79.00 | 2 | |
Metformin activates AMP-activated protein kinase (AMPK), a key regulator of energy metabolism. MUP is implicated in cellular responses to energy stress. Metformin-induced AMPK activation indirectly modulates MUP by altering energy-sensing pathways. The resulting changes in AMPK activity can influence MUP-mediated responses to metabolic stress and energy homeostasis, impacting cellular processes related to lipid metabolism and AMPK signaling. | ||||||
L-3,3′,5-Triiodothyronine, free acid | 6893-02-3 | sc-204035 sc-204035A sc-204035B | 10 mg 100 mg 250 mg | $41.00 $77.00 $153.00 | ||
Thyroid Hormone (T3) activates thyroid hormone receptors (TR) signaling. MUP is associated with thyroid hormone signaling. T3-induced TR activation enhances MUP function by influencing its interactions with signaling components, leading to altered cellular responses to thyroid hormone signaling and impacting MUP-mediated processes. | ||||||
Ob (hBA-147) | sc-4912 | 1000 µg | $258.00 | 1 | ||
Ob (hBA-147) activates the Janus kinase-signal transducer and activator of transcription (JAK-STAT) signaling pathway. MUP is associated with leptin-mediated signaling events. | ||||||
Clofibrate | 637-07-0 | sc-200721 | 1 g | $33.00 | ||
Fibrates, such as Clofibrate, activate peroxisome proliferator-activated receptor alpha (PPARα), a transcription factor involved in lipid metabolism. MUP is associated with PPARα-mediated signaling pathways. Clofibrate-induced PPARα activation enhances MUP function by influencing its interactions with signaling components, leading to altered cellular responses to lipid metabolism and PPARα signaling, ultimately impacting MUP-mediated processes. | ||||||