Mucin 15 Inhibitors

Mucins are large, heavily glycosylated proteins that play crucial roles in protecting and lubricating mucosal surfaces, such as those lining the gastrointestinal tract, respiratory system, and other mucous membranes throughout the body. Mucin 15, also known as MUC15, is a specific member of the mucin family that has been identified in various tissues and organs, and its functions are not yet fully understood. It is characterized by its extensive glycosylation, which contributes to its protective properties in mucosal tissues. Mucin 15 inhibitors modulate the activity of MUC15, potentially interfering with its functions. These inhibitors have the potential to influence the glycosylation patterns and structural properties of MUC15, which could, in turn, impact its interactions with other molecules and its roles in mucosal protection and lubrication. Researchers employ Mucin 15 inhibitors as valuable tools to investigate the specific functions and regulatory mechanisms of MUC15 in different cellular contexts and tissues.