Mts1 Inhibitors
Mts1 inhibitors belong to a specific class of chemical compounds that are primarily designed to target and modulate the activity of Mts1, also known as S100A4, a calcium-binding protein with significant implications in various cellular processes. Mts1 is a member of the S100 family of proteins, which play essential roles in regulating cell proliferation, migration, invasion, and angiogenesis. In particular, Mts1 has garnered considerable attention in the context of cancer research due to its involvement in promoting metastasis, the process by which cancer cells spread from the primary tumor to distant organs, ultimately leading to the majority of cancer-related deaths. Consequently, the development of Mts1 inhibitors has emerged as a critical avenue in the pursuit of novel strategies for combating cancer progression.
Mts1 inhibitors are designed to interact with Mts1 protein directly or disrupt its functional interactions with other cellular components, thereby interfering with its role in facilitating metastatic processes. These inhibitors are typically small molecules that can be synthesized through various chemical methods. The goal is to block or modulate the functions of Mts1, such as its ability to bind to other proteins, like non-muscle myosin IIA, which is crucial for promoting cell motility and invasion. By targeting Mts1, these inhibitors aim to impede the metastatic abilities of cancer cells, reducing their ability to spread to distant sites in the body. Researchers continue to explore the development and optimization of Mts1 inhibitors as part of the ongoing efforts to understand and combat cancer metastasis, which remains a major challenge in the field of oncology.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A is a histone deacetylase inhibitor that can alter gene expression by affecting chromatin structure, potentially decreasing Mts1 expression by promoting a closed chromatin configuration. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
As a DNA methyltransferase inhibitor, 5-Azacytidine can lead to the demethylation and reactivation of silenced genes, which might indirectly inhibit Mts1 expression through epigenetic modulation. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
Bortezomib, a proteasome inhibitor, may affect Mts1 expression indirectly through the stabilization of cellular proteins that regulate gene expression and signal transduction pathways linked to Mts1. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin is known to modulate multiple cell-signaling pathways; it may suppress Mts1 expression by interfering with transcription factors and signaling pathways that upregulate Mts1. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol has been shown to influence gene expression and protein synthesis, which may include downregulation of Mts1 expression through the modulation of signal transduction pathways. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin may inhibit Mts1 expression by modulating signaling pathways and transcription factors involved in cell cycle regulation and proliferation. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Caffeine can influence a variety of intracellular signaling pathways, potentially leading to the downregulation of Mts1 expression as part of its broad effects on cellular processes. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Suberoylanilide Hydroxamic Acid, a histone deacetylase inhibitor, may affect gene expression, potentially reducing Mts1 levels by altering the chromatin structure and thus transcriptional regulation of the Mts1 gene. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $43.00 $63.00 $156.00 $260.00 $510.00 $31.00 | 37 | |
1,1-Dimethylbiguanide, Hydrochloride is known to exert effects on cellular metabolism that could extend to the modulation of gene expression, possibly including a reduction in Mts1 expression through indirect metabolic pathways. | ||||||
hydroxychloroquine | 118-42-3 | sc-507426 | 5 g | $57.00 | 1 | |
Hydroxychloroquine, through its broad immunomodulatory and anti-inflammatory effects, may influence various signaling pathways and transcription factors, which could result in decreased expression of Mts1. | ||||||