Mel13 inhibitors constitute a specific class of compounds that target the Mel13 protein, which plays a pivotal role in various cellular processes, particularly those related to chromatin remodeling and gene expression regulation. Mel13 is known to be involved in modulating the activity of specific transcription factors and influencing the accessibility of DNA to the transcriptional machinery. The inhibitors are designed to bind selectively to the Mel13 protein, thereby obstructing its function and disrupting its interactions with other molecular partners. This targeted approach allows researchers to delve deeper into the biochemical pathways governed by Mel13, offering insights into its structural dynamics and regulatory mechanisms.
In research settings, the application of Mel13 inhibitors facilitates the investigation of gene regulation and chromatin dynamics under different cellular conditions. By inhibiting Mel13, scientists can observe changes in gene expression patterns and chromatin structure, providing a clearer understanding of how this protein influences cellular responses. Additionally, these inhibitors help elucidate the broader role of chromatin-associated proteins in cellular development and differentiation processes. The versatility of Mel13 inhibitors makes them valuable tools for exploring fundamental biological questions, particularly in the context of gene expression modulation and chromatin architecture. As research progresses, the ongoing study of Mel13 inhibitors is expected to contribute significantly to our comprehension of the intricate networks that govern cellular function and gene regulation.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Dimethyl fumarate | 624-49-7 | sc-239774 | 25 g | $27.00 | 6 | |
Dimethyl fumarate is an electrophilic agent that can modify cysteine residues in proteins, potentially altering the iron-sulfur cluster assembly process. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Staurosporine is a potent inhibitor of protein kinases and may interfere with the phosphorylation states of proteins involved in iron-sulfur cluster assembly. | ||||||
Clioquinol | 130-26-7 | sc-201066 sc-201066A | 1 g 5 g | $44.00 $113.00 | 2 | |
Clioquinol is a metal chelator that can bind to iron and may disrupt the iron availability necessary for [2Fe-2S] cluster formation. | ||||||
Sodium molybdate | 7631-95-0 | sc-236912 sc-236912A sc-236912B | 5 g 100 g 500 g | $55.00 $82.00 $316.00 | 1 | |
Sodium molybdate can compete with iron-sulfur clusters for binding to proteins and may inhibit the transfer of [2Fe-2S] clusters. | ||||||
Methylene blue | 61-73-4 | sc-215381B sc-215381 sc-215381A | 25 g 100 g 500 g | $42.00 $102.00 $322.00 | 3 | |
Methylene blue is a redox-active compound that can accept electrons from iron-sulfur clusters, potentially disrupting their function. | ||||||
Auranofin | 34031-32-8 | sc-202476 sc-202476A sc-202476B | 25 mg 100 mg 2 g | $150.00 $210.00 $1899.00 | 39 | |
Auranofin is a gold-containing compound that can interact with thiol groups in proteins, potentially affecting the cysteine ligands that bind [2Fe-2S] clusters. | ||||||
Cadmium chloride, anhydrous | 10108-64-2 | sc-252533 sc-252533A sc-252533B | 10 g 50 g 500 g | $55.00 $179.00 $345.00 | 1 | |
Cadmium chloride is a heavy metal salt that can replace iron in sulfur clusters, leading to dysfunctional iron-sulfur proteins. | ||||||
Silver nitrate | 7761-88-8 | sc-203378 sc-203378A sc-203378B | 25 g 100 g 500 g | $112.00 $371.00 $1060.00 | 1 | |
Silver nitrate can bind to thiol groups and may interfere with the cysteine residues that coordinate [2Fe-2S] clusters. | ||||||
Lead(II) Acetate | 301-04-2 | sc-507473 | 5 g | $83.00 | ||
Lead acetate is a heavy metal compound that can disrupt protein structure and function, including those proteins involved in iron-sulfur cluster assembly. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc sulfate can bind to sulfur donor molecules, potentially outcompeting iron and interrupting [2Fe-2S] cluster assembly. |