Date published: 2025-9-10

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Mel13 Inhibitors

Mel13 inhibitors constitute a specific class of compounds that target the Mel13 protein, which plays a pivotal role in various cellular processes, particularly those related to chromatin remodeling and gene expression regulation. Mel13 is known to be involved in modulating the activity of specific transcription factors and influencing the accessibility of DNA to the transcriptional machinery. The inhibitors are designed to bind selectively to the Mel13 protein, thereby obstructing its function and disrupting its interactions with other molecular partners. This targeted approach allows researchers to delve deeper into the biochemical pathways governed by Mel13, offering insights into its structural dynamics and regulatory mechanisms.

In research settings, the application of Mel13 inhibitors facilitates the investigation of gene regulation and chromatin dynamics under different cellular conditions. By inhibiting Mel13, scientists can observe changes in gene expression patterns and chromatin structure, providing a clearer understanding of how this protein influences cellular responses. Additionally, these inhibitors help elucidate the broader role of chromatin-associated proteins in cellular development and differentiation processes. The versatility of Mel13 inhibitors makes them valuable tools for exploring fundamental biological questions, particularly in the context of gene expression modulation and chromatin architecture. As research progresses, the ongoing study of Mel13 inhibitors is expected to contribute significantly to our comprehension of the intricate networks that govern cellular function and gene regulation.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Dimethyl fumarate

624-49-7sc-239774
25 g
$27.00
6
(1)

Dimethyl fumarate is an electrophilic agent that can modify cysteine residues in proteins, potentially altering the iron-sulfur cluster assembly process.

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$82.00
$150.00
$388.00
113
(4)

Staurosporine is a potent inhibitor of protein kinases and may interfere with the phosphorylation states of proteins involved in iron-sulfur cluster assembly.

Clioquinol

130-26-7sc-201066
sc-201066A
1 g
5 g
$44.00
$113.00
2
(1)

Clioquinol is a metal chelator that can bind to iron and may disrupt the iron availability necessary for [2Fe-2S] cluster formation.

Sodium molybdate

7631-95-0sc-236912
sc-236912A
sc-236912B
5 g
100 g
500 g
$55.00
$82.00
$316.00
1
(0)

Sodium molybdate can compete with iron-sulfur clusters for binding to proteins and may inhibit the transfer of [2Fe-2S] clusters.

Methylene blue

61-73-4sc-215381B
sc-215381
sc-215381A
25 g
100 g
500 g
$42.00
$102.00
$322.00
3
(1)

Methylene blue is a redox-active compound that can accept electrons from iron-sulfur clusters, potentially disrupting their function.

Auranofin

34031-32-8sc-202476
sc-202476A
sc-202476B
25 mg
100 mg
2 g
$150.00
$210.00
$1899.00
39
(2)

Auranofin is a gold-containing compound that can interact with thiol groups in proteins, potentially affecting the cysteine ligands that bind [2Fe-2S] clusters.

Cadmium chloride, anhydrous

10108-64-2sc-252533
sc-252533A
sc-252533B
10 g
50 g
500 g
$55.00
$179.00
$345.00
1
(1)

Cadmium chloride is a heavy metal salt that can replace iron in sulfur clusters, leading to dysfunctional iron-sulfur proteins.

Silver nitrate

7761-88-8sc-203378
sc-203378A
sc-203378B
25 g
100 g
500 g
$112.00
$371.00
$1060.00
1
(1)

Silver nitrate can bind to thiol groups and may interfere with the cysteine residues that coordinate [2Fe-2S] clusters.

Lead(II) Acetate

301-04-2sc-507473
5 g
$83.00
(0)

Lead acetate is a heavy metal compound that can disrupt protein structure and function, including those proteins involved in iron-sulfur cluster assembly.

Zinc

7440-66-6sc-213177
100 g
$47.00
(0)

Zinc sulfate can bind to sulfur donor molecules, potentially outcompeting iron and interrupting [2Fe-2S] cluster assembly.