MCR Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Canrenone | 976-71-6 | sc-205616 sc-205616A | 1 g 5 g | $94.00 $333.00 | 3 | |
Canrenone acts as a modulator of mineralocorticoid receptor activity, distinguished by its capacity to form stable complexes through hydrogen bonding and hydrophobic interactions. Its unique structural features facilitate selective binding, leading to altered receptor dynamics and downstream signaling pathways. The compound exhibits a notable affinity for specific conformational states, influencing the kinetics of receptor activation and subsequent cellular responses, thereby impacting various physiological processes. | ||||||
Spironolactone | 52-01-7 | sc-204294 | 50 mg | $109.00 | 3 | |
Spironolactone functions as a mineralocorticoid receptor modulator, characterized by its ability to engage in specific molecular interactions that stabilize receptor conformations. Its unique steric configuration allows for selective binding, promoting distinct allosteric effects that influence receptor activity. The compound's kinetic profile reveals a nuanced interaction with the receptor, affecting the rate of activation and the subsequent signaling cascade, ultimately shaping cellular behavior in a targeted manner. | ||||||
Eplerenone | 107724-20-9 | sc-203943 sc-203943A | 10 mg 50 mg | $110.00 $624.00 | 4 | |
Eplerenone acts as a mineralocorticoid receptor modulator, distinguished by its selective affinity for the receptor's ligand-binding domain. Its unique structural features facilitate specific hydrogen bonding and hydrophobic interactions, enhancing receptor selectivity. The compound exhibits a distinct kinetic behavior, influencing the rate of receptor activation and downstream signaling pathways. This modulation leads to a finely tuned response in cellular processes, reflecting its intricate molecular dynamics. | ||||||
Guggulsterone | 95975-55-6 | sc-203990 sc-203990A | 10 mg 50 mg | $145.00 $615.00 | 1 | |
Guggulsterone functions as a modulator of nuclear receptors, characterized by its ability to engage in specific hydrophobic interactions and conformational changes within the receptor structure. Its unique steric configuration allows for selective binding, influencing the receptor's transcriptional activity. The compound's dynamic molecular interactions contribute to its distinct regulatory effects on gene expression, showcasing its complex role in cellular signaling pathways. | ||||||
RU 28318, potassium salt | 76676-34-1 | sc-204250 sc-204250A | 5 mg 10 mg | $510.00 $928.00 | ||
RU 28318, potassium salt, exhibits unique reactivity as a multi-component reaction (MCR) facilitator, promoting the formation of diverse molecular architectures. Its ionic nature enhances solubility and facilitates rapid intermolecular interactions, leading to efficient reaction kinetics. The compound's ability to stabilize transition states through electrostatic interactions allows for the formation of complex products, showcasing its versatility in synthetic pathways and enhancing reaction yields. | ||||||
Spironolactone-d7 (Major) | 52-01-7 (unlabeled) | sc-220132 sc-220132A | 1 mg 10 mg | $290.00 $2000.00 | ||
Spironolactone-d7 (Major) serves as a distinctive multi-component reaction (MCR) agent, characterized by its isotopic labeling that enables precise tracking of molecular transformations. Its unique steric and electronic properties influence reaction selectivity, promoting specific pathways while minimizing side reactions. The compound's ability to engage in hydrogen bonding and π-π stacking interactions enhances the stability of intermediates, resulting in improved reaction efficiency and product diversity. | ||||||
7-Aminoindole | 5192-04-1 | sc-257005 | 1 g | $555.00 | ||
7-Aminoindole is a versatile multi-component reaction (MCR) agent known for its unique ability to facilitate complex molecular formations through diverse reaction pathways. Its electron-rich indole structure allows for strong π-π interactions, enhancing the stability of transition states. Additionally, the presence of the amino group promotes nucleophilic reactivity, enabling efficient coupling with electrophiles. This compound's distinctive sterics and electronics contribute to its role in generating a wide array of products with varied functionalization. | ||||||