MBD3 Activators
MBD3 (Methyl-CpG Binding Domain Protein 3) activators represent a class of compounds that play a crucial role in the field of molecular biology and epigenetics. MBD3 is a member of the MBD protein family, which is primarily known for its involvement in interpreting epigenetic information encoded in DNA methylation patterns. MBD3, specifically, is essential for regulating gene expression by binding to methylated regions of DNA, which are often associated with gene silencing. MBD3 activators are chemical compounds that modulate the activity of MBD3, thereby influencing the epigenetic landscape and gene expression patterns within cells.
The mechanism of action of MBD3 activators typically involves the binding of these compounds to MBD3 proteins, leading to conformational changes that enhance MBD3's ability to recognize and interact with methylated DNA sequences. By doing so, MBD3 activators can influence chromatin remodeling and gene transcription processes, ultimately affecting the expression of specific genes. Researchers have been particularly interested in MBD3 activators due to their potential in unraveling the complex mechanisms of epigenetic regulation and gene expression. Understanding how these compounds modulate MBD3 activity can shed light on fundamental biological processes and may have implications in various fields, such as developmental biology, cell differentiation, and disease mechanisms.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Valproic Acid is known as a histone deacetylase inhibitor. By inhibiting the removal of acetyl groups from histones, it leads to a more open chromatin structure, potentially facilitating the transcription of various genes, including MBD3. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A is another histone deacetylase inhibitor, and it functions similarly to Valproic Acid. It can change chromatin structure and activate gene transcription, possibly affecting MBD3 expression levels. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium Butyrate serves as a histone deacetylase inhibitor. By maintaining histones in an acetylated state, it encourages an open chromatin configuration, possibly enhancing the expression of certain genes, such as MBD3. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid is known to influence gene expression and cell differentiation. It might induce the expression of specific genes, including MBD3, through its interaction with retinoic acid receptors and modification of chromatin structure. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
This compound, found in green tea, has been shown to have various biological effects, including epigenetic modulation. It might affect the expression of certain genes, possibly including MBD3, through changes in DNA methylation and histone modification. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein, a soy isoflavone, has been studied for its ability to modulate epigenetic marks. It might influence the expression of various genes, including MBD3, through its effects on DNA methylation and histone modification. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, found in turmeric, has been studied for its epigenetic modulating capabilities. It might impact gene expression, potentially including MBD3, through alterations in DNA methylation and histone acetylation patterns. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Found in grapes and berries, Resveratrol has potential epigenetic modulating effects. It might influence the expression of various genes, potentially including MBD3, through mechanisms involving DNA methylation and histone modification. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane, found in cruciferous vegetables, has shown potential in epigenetic modulation. It might affect the expression of certain genes, potentially including MBD3, through its impact on DNA methylation and histone acetylation. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc is an essential mineral that plays roles in various biological processes. While its direct impact on MBD3 expression is less clear, it is involved in DNA synthesis and cell division, and it might influence gene expression through various indirect pathways. | ||||||