Lysozyme C Activators
Lysozyme C is an antimicrobial enzyme extensively studied for its role in the innate immune system, primarily found in saliva, mucus, human milk, and white blood cells. It functions by cleaving the glycosidic bonds in the peptidoglycan layer of bacterial cell walls, which leads to the bacterium's osmotic lysis. This enzymatic activity is crucial for the body's first line of defense against bacterial infections. The mechanism of action of Lysozyme C involves the hydrolysis of the β(1→4) glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan, a major component of the bacterial cell wall. This action effectively weakens the cell wall and leads to the cell's rupture under its internal osmotic pressure, thus playing a vital role in inhibiting bacterial growth.
The activation of Lysozyme C can be influenced by various factors, including ionic strength, pH, and the presence of specific ions or molecules that can stabilize the enzyme's structure or enhance its interaction with the substrate. Although direct chemical activators of Lysozyme C are not explicitly documented, indirect activation can occur through the stabilization of the enzyme's structure, enhancing its substrate affinity, or altering the cellular or extracellular environment to facilitate its enzymatic action. The chemicals listed above have been selected based on their potential to create conditions favorable for the enzymatic activity of Lysozyme C or to stabilize the enzyme itself, thereby indirectly enhancing its antibacterial function. The activation mechanisms vary from stabilizing the enzyme's tertiary structure, acting as a cofactor to enhance its activity, to altering the osmotic environment, making bacterial cells more susceptible to Lysozyme C's action. This indirect approach to activation highlights the complexity of enzymatic regulation and the potential for multifaceted intervention strategies to enhance enzyme function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Magnesium sulfate anhydrous | 7487-88-9 | sc-211764 sc-211764A sc-211764B sc-211764C sc-211764D | 500 g 1 kg 2.5 kg 5 kg 10 kg | $46.00 $69.00 $163.00 $245.00 $418.00 | 3 | |
Magnesium Sulfate is crucial for maintaining ionic balance and enzyme stability. It stabilizes the tertiary and quaternary structures of proteins, potentially activating Lysozyme C by ensuring its structural integrity for optimal enzymatic function. | ||||||
Zinc sulfate solution | 7733-02-0 | sc-251451 | 250 ml | $112.00 | ||
Zinc Sulfate is known to play a role in enzyme stabilization and activation. It may activate Lysozyme C by acting as a cofactor, enhancing its antibacterial enzymatic activity by promoting the correct folding and structural stability necessary for its action. | ||||||
Glycerol | 56-81-5 | sc-29095A sc-29095 | 100 ml 1 L | $56.00 $153.00 | 12 | |
Glycerol is used in protein purification to stabilize proteins against denaturation. It can indirectly activate Lysozyme C by maintaining its conformational stability, ensuring the enzyme remains in an active form ready to cleave bacterial cell walls. | ||||||
Dimethyl Sulfoxide (DMSO) | 67-68-5 | sc-202581 sc-202581A sc-202581B | 100 ml 500 ml 4 L | $31.00 $117.00 $918.00 | 136 | |
Dimethyl sulfoxide (DMSO) facilitates the crossing of compounds through biological membranes. It can activate Lysozyme C indirectly by increasing cell membrane permeability, enhancing the delivery of Lysozyme C to its site of action against bacteria. | ||||||
Urea | 57-13-6 | sc-29114 sc-29114A sc-29114B | 1 kg 2 kg 5 kg | $31.00 $43.00 $78.00 | 17 | |
Urea at low concentrations can stabilize proteins. It potentially activates Lysozyme C by preserving its structure, ensuring that Lysozyme C maintains its activity against bacterial cell walls. | ||||||
L-Arginine | 74-79-3 | sc-391657B sc-391657 sc-391657A sc-391657C sc-391657D | 5 g 25 g 100 g 500 g 1 kg | $20.00 $31.00 $61.00 $219.00 $352.00 | 2 | |
Arginine can act as a stabilizer for proteins and enzymes. It may activate Lysozyme C by ensuring its structural stability, which is essential for its enzymatic activity against bacterial cell walls. | ||||||
D(+)Glucose, Anhydrous | 50-99-7 | sc-211203 sc-211203B sc-211203A | 250 g 5 kg 1 kg | $38.00 $198.00 $65.00 | 5 | |
Glucose can influence osmotic balance and energy supply. It indirectly activates Lysozyme C by providing an optimal osmotic environment for lysozyme release and activity against bacterial pathogens. | ||||||
Sucrose | 57-50-1 | sc-204311 sc-204311B sc-204311C sc-204311A | 0.5 kg 50 kg 100 kg 5 kg | $58.00 $2000.00 $3500.00 $250.00 | 6 | |
Sucrose is used to stabilize proteins during freeze-drying. It can indirectly activate Lysozyme C by maintaining its active structure, enhancing its ability to degrade bacterial cell walls. | ||||||
Calcium chloride anhydrous | 10043-52-4 | sc-207392 sc-207392A | 100 g 500 g | $66.00 $262.00 | 1 | |
Calcium Chloride can enhance enzyme stability and activity. It activates Lysozyme C by potentially stabilizing its active site structure, promoting its bacteriolytic activity on the cell walls of bacteria. | ||||||