Date published: 2026-4-24

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LASS2 Inhibitors

LASS2 inhibitors constitute a specific chemical class of compounds designed to target the Longevity Assurance Gene 2 (LASS2), an enzyme involved in sphingolipid metabolism. These inhibitors are carefully developed to interact with LASS2 at the molecular level, with the aim of modulating its enzymatic activity. By inhibiting LASS2, researchers seek to gain insights into the complex processes of sphingolipid biosynthesis and signaling. The chemical structures of LASS2 inhibitors can vary, and they are designed to interact with specific binding sites or regions of LASS2, thereby interfering with its substrate binding and catalytic functions.

Investigating LASS2 inhibitors is essential for advancing our understanding of the roles of sphingolipids in various cellular processes, including apoptosis and cancer progression. This research contributes to the broader knowledge of sphingolipid metabolism and its relevance in cellular physiology. As research in this field progresses, additional LASS2 inhibitors may be identified and characterized, providing valuable insights into the intricate regulation of sphingolipid pathways and potential applications in cellular and molecular biology research.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

C-8 Ceramide

74713-59-0sc-205233
sc-205233A
sc-205233B
1 mg
5 mg
25 mg
$19.00
$63.00
$228.00
1
(0)

Synthetic compounds that mimic the structure of ceramide, a product of LASS2 activity, can inhibit LASS2 function by competing for substrate binding.

Myriocin (ISP-1)

35891-70-4sc-201397
10 mg
$150.00
8
(2)

A fungal metabolite that inhibits LASS2 and other enzymes involved in sphingolipid biosynthesis.

Fumonisin B1

116355-83-0sc-201395
sc-201395A
1 mg
5 mg
$200.00
$680.00
18
(1)

A mycotoxin that inhibits LASS2 and disrupts sphingolipid metabolism.

Desipramine hydrochloride

58-28-6sc-200158
sc-200158A
100 mg
1 g
$66.00
$117.00
6
(2)

A tricyclic antidepressant that has been shown to inhibit LASS2 activity.

D609

83373-60-8sc-201403
sc-201403A
5 mg
25 mg
$189.00
$575.00
7
(1)

A xanthogenate compound that inhibits LASS2 and other enzymes in the sphingolipid biosynthesis pathway.

4-Hydroxyphenylretinamide

65646-68-6sc-200900
sc-200900A
5 mg
25 mg
$104.00
$315.00
(0)

A synthetic retinoid compound that can inhibit LASS2 in cancer cells.