KRT222 Activators

Keratin 222 (KRT222) is part of the keratin family, a diverse group of structural proteins that are key components of the intermediate filament network in epithelial cells. Keratins are known for their structural role in providing mechanical stability and resilience to cells and tissues. They are divided into two types: type I (acidic) and type II (basic to neutral), which form heterodimers and then polymers to create the intermediate filament network. KRT222, specifically, falls within this broad family, contributing to the structural integrity and function of epithelial cells.

Activators of KRT222, if they were characterized, would be chemical compounds or molecules that specifically enhance or modulate the function or expression of KRT222. These activators might operate by interacting at the genetic level to increase the transcription of the KRT222 gene, or at the protein level to stabilize the keratin filament network, enhancing its structural properties. In the context of cellular biology, the regulation of keratin expression and function is crucial for maintaining the proper structure and resilience of epithelial tissues.