Keratin 6B activators belong to a unique category of chemical agents that specifically target and modulate the activity of Keratin 6B, a type of keratin protein. Keratin 6B is one of the many keratins, a family of fibrous structural proteins that are key components of the cytoskeleton of epithelial cells. It plays a crucial role in the integrity and function of certain types of epithelial tissues. The specific function of Keratin 6B in the cellular structure and its significance in maintaining the mechanical stability and resilience of epithelial cells make the study of its activators particularly interesting. These activators interact with Keratin 6B at a molecular level, affecting its expression, assembly, and integration into the cellular cytoskeleton. This interaction is important for understanding the dynamics of keratin-based structures within cells, and how these structures can be modulated. The precise mechanism by which Keratin 6B activators influence the protein involves a complex interplay of molecular interactions, potentially altering the protein's conformation, stability, and its interactions with other cellular components.
From a chemical perspective, Keratin 6B activators are comprised of complex organic compounds, often characterized by the presence of specific functional groups that facilitate targeted interactions with keratin proteins. Their molecular structure is intricately designed to enable efficient and specific binding to Keratin 6B. This specificity is crucial for their ability to modulate the protein in a controlled manner. The interactions between these activators and Keratin 6B can lead to changes in the keratin's properties, such as alterations in its filament organization, mechanical strength, and interaction with other cellular structures. Understanding the behavior of these activators at the molecular level is essential for unraveling the complex mechanisms that regulate keratin proteins like Keratin 6B within cells. The study of Keratin 6B activators contributes significantly to the fields of cell biology and biochemistry, providing insights into the intricate processes that govern the structural and functional dynamics of epithelial cells. This research enhances our comprehension of the molecular basis of cell structure and function, particularly in the context of keratin-rich tissues.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
All-trans retinoic acid can modulate gene expression by activating retinoic acid receptors, which may lead to the upregulation of keratin genes. | ||||||
Hydrocortisone | 50-23-7 | sc-300810 | 5 g | $100.00 | 6 | |
Hydrocortisone binds to glucocorticoid receptors, potentially influencing the transcription of target genes, including keratins, in certain contexts. | ||||||
Minoxidil (U-10858) | 38304-91-5 | sc-200984 sc-200984A | 100 mg 1 g | $68.00 $344.00 | ||
Minoxidil may indirectly affect keratin expression as it is known to stimulate hair growth possibly by affecting follicular keratinocytes. | ||||||
13-cis-Retinoic acid | 4759-48-2 | sc-205568 sc-205568A | 100 mg 250 mg | $74.00 $118.00 | 8 | |
Isotretinoin, a retinoid derivative, could influence keratin gene expression through its action on retinoid receptors in the skin. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Vitamin D3 through its hormonal form can bind to vitamin D receptors, influencing the expression of various genes including keratins. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $92.00 $209.00 | 33 | |
Methotrexate impacts cell proliferation and may lead to compensatory mechanisms that involve the upregulation of structural proteins like keratins. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 5 g 100 g 250 g 1 kg 5 kg | $32.00 $66.00 $95.00 $188.00 $760.00 | 13 | |
Caffeine has been shown to influence various cellular pathways and might affect keratin expression through its signaling effects. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $43.00 $65.00 $200.00 $815.00 | 6 | |
Nicotinamide, a form of vitamin B3, may play a role in skin cell metabolism and could potentially influence keratin gene expression. | ||||||
Tazarotene | 118292-40-3 | sc-220193 | 10 mg | $103.00 | ||
Tazarotene is a retinoid prodrug that modulates gene expression and could upregulate keratin genes as part of its effect on epidermal differentiation. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane, a compound found in cruciferous vegetables, is known to affect gene expression through epigenetic mechanisms which could include keratins. | ||||||