ITI-H1 Activators
The potential activators for ITI-H1 reflect a broad spectrum of compounds that indirectly influence its functional activity through modulation of cellular pathways, gene expression regulation, and extracellular matrix interactions. Retinoic Acid, all trans and Dexamethasone are recognized for their roles in modulating gene expression and inflammation, respectively. Retinoic Acid, all trans, through its receptor-mediated gene regulation, might enhance ITIH1 expression in contexts of tissue repair and inflammation where ITIH1 plays a critical role. Dexamethasone, as a potent anti-inflammatory agent, could upregulate ITIH1 expression as part of the body's acute phase response, contributing to inflammation resolution and tissue stabilization. L-Ascorbic acid, free acid's involvement in collagen synthesis and extracellular matrix stability might also support the function of ITIH1, given its role in matrix stabilization through interaction with hyaluronan.
Additionally, compounds like Sodium phenylbutyrate, Betaine, and Ursolic Acid, with various effects on cellular metabolism, stress responses, and inflammation, might also modulate ITIH1 activity. Sodium phenylbutyrate, through its influence on gene expression and protein stabilization, and Betaine, as an osmolyte and methyl donor, might indirectly affect ITIH1's function in maintaining extracellular matrix stability. Ursolic Acid, recognized for its anti-inflammatory properties, could further modulate ITIH1 activity in the context of tissue inflammation and repair, enhancing its role in stabilizing the extracellular matrix and modulating acute phase responses. Collectively, these compounds, through indirect and multifaceted mechanisms, highlight the potential complexity in modulating the activity of ITIH1, reflecting its importance in extracellular matrix stability, inflammation, and tissue repair processes.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Known to regulate gene expression by activating nuclear receptors; might enhance ITIH1 expression or stability by influencing inflammation and tissue repair pathways where ITIH1 is involved. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
A synthetic glucocorticoid that acts as an anti-inflammatory and immunosuppressant; it could potentially upregulate ITIH1 expression as part of the acute phase response or modulate its activity in tissue repair and inflammation. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $45.00 | 5 | |
Known to play a role in collagen synthesis and might influence the stability of the extracellular matrix and associated proteins like ITIH1. | ||||||
Hyaluronic acid | 9004-61-9 | sc-337865 | 10 mg | $204.00 | ||
As a major component of the extracellular matrix with which ITIH1 interacts, supplementation might indirectly influence ITIH1 activity or stability by altering the extracellular matrix composition or enhancing the interaction between ITIH1 and hyaluronan. | ||||||
Sodium phenylbutyrate | 1716-12-7 | sc-200652 sc-200652A sc-200652B sc-200652C sc-200652D | 1 g 10 g 100 g 1 kg 10 kg | $75.00 $163.00 $622.00 $4906.00 $32140.00 | 43 | |
Used for its effects on gene expression and protein stabilization; might enhance ITIH1 activity or expression through its influence on cellular stress responses and gene regulation. | ||||||
Betaine | 107-43-7 | sc-214595 sc-214595A sc-214595B sc-214595C sc-214595D sc-214595E | 50 g 100 g 250 g 1 kg 2.5 kg 5 kg | $30.00 $40.00 $55.00 $160.00 $330.00 $580.00 | 2 | |
Known as an osmolyte and methyl donor, betaine might influence ITIH1 expression or activity indirectly through its effects on cellular metabolism and stress responses. | ||||||
Ursolic Acid | 77-52-1 | sc-200383 sc-200383A | 50 mg 250 mg | $55.00 $176.00 | 8 | |
A natural compound found in apple peels, known for its anti-inflammatory properties; could potentially modulate ITIH1 expression or activity in the context of tissue inflammation and repair. | ||||||