HYAL5 inhibitors belong to a class of chemical compounds designed to target and interfere with the activity of the HYAL5 protein. HYAL5, or Hyaluronidase-like 5, is an enzyme that is part of the hyaluronidase family. These enzymes are known for their involvement in the degradation of hyaluronic acid, a large glycosaminoglycan found in the extracellular matrix and various tissues in the body. HYAL5, specifically, is thought to play a role in hyaluronic acid metabolism and may be implicated in processes related to tissue homeostasis and cellular interactions with the extracellular matrix.
The mode of action for HYAL5 inhibitors typically involves their interaction with the HYAL5 protein or its associated molecules, interfering with its enzymatic activity. By inhibiting HYAL5, these compounds may modulate the degradation of hyaluronic acid, potentially affecting the properties of the extracellular matrix and cell behavior. Researchers studying HYAL5 inhibitors aim to better understand the specific functions of HYAL5 in tissue biology, extracellular matrix dynamics, and cellular responses. These inhibitors serve as valuable tools for advancing our knowledge of the role of HYAL5 in various biological processes. In this context, they contribute to our understanding of the complex interplay between enzymes and the extracellular matrix within the broader field of molecular and cellular biology.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
A compound from turmeric that may modulate transcription factor activity, potentially downregulating HYAL5 expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
A polyphenol that could influence gene expression through sirtuin activation, potentially affecting HYAL5 levels. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Found in cruciferous vegetables, may act epigenetically to inhibit histone deacetylase, possibly affecting HYAL5 expression. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
An isoflavone that may inhibit tyrosine kinases and affect transcription factors regulating genes like HYAL5. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
A flavonoid that may modify gene expression through its action as an antioxidant and potential signaling pathway modulator. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
The main catechin in green tea, could potentially modulate gene expression through epigenetic mechanisms. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
A metabolite of vitamin A that regulates gene expression by activating retinoic acid receptors, potentially affecting HYAL5. | ||||||
Aspirin | 50-78-2 | sc-202471 sc-202471A | 5 g 50 g | $20.00 $41.00 | 4 | |
Also known as aspirin, may modulate NF-κB pathway and influence gene expression, possibly downregulating HYAL5. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
A short-chain fatty acid derivative that acts as an HDAC inhibitor, potentially affecting gene expression like HYAL5. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
A glucocorticoid that regulates gene expression through glucocorticoid receptor activation, potentially downregulating HYAL5. |