Date published: 2025-10-25

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HRPAP20 Inhibitors

HRPAP20 Inhibitors belong to a specialized category of chemical compounds developed for the specific purpose of targeting and modulating the activity of HRPAP20, which stands for Heme-Responsive Protein Associated with a Protein of 20 kDa. HRPAP20 is a protein that has drawn scientific interest due to its responsiveness to heme, a vital molecule involved in various biological processes, including oxygen transport, cellular respiration, and gene regulation. While the exact functions of HRPAP20 are still being elucidated, its ability to respond to heme suggests a role in heme-related pathways. Inhibitors of HRPAP20 are meticulously designed to interact with this protein, potentially influencing its binding to heme or other molecular partners, cellular localization, or participation in processes where HRPAP20 plays a role.

Structurally, HRPAP20 inhibitors are crafted to engage specific regions or binding sites on the HRPAP20 protein. This interaction may disrupt the normal functioning of HRPAP20, potentially affecting its responsiveness to heme or its involvement in heme-associated processes. The mechanisms through which HRPAP20 inhibitors exert their effects can vary, but their primary purpose is to serve as valuable tools for researchers investigating the roles of HRPAP20 in heme metabolism and other biological contexts. By studying the biochemical and functional aspects of HRPAP20 and its modulation by inhibitors, researchers can gain insights into the intricate mechanisms governing heme-related pathways, gene expression regulation, and cellular responses to changes in heme levels, contributing to our understanding of fundamental molecular processes within cells.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Rotenone

83-79-4sc-203242
sc-203242A
1 g
5 g
$89.00
$254.00
41
(1)

Rotenone is a known inhibitor of mitochondrial complex I and can disrupt the electron transport chain.

Antimycin A

1397-94-0sc-202467
sc-202467A
sc-202467B
sc-202467C
5 mg
10 mg
1 g
3 g
$54.00
$62.00
$1642.00
$4600.00
51
(1)

Antimycin A inhibits mitochondrial complex III, which could have downstream effects on complex I function.

Oligomycin

1404-19-9sc-203342
sc-203342C
10 mg
1 g
$146.00
$12250.00
18
(2)

Oligomycin inhibits ATP synthase, potentially affecting overall mitochondrial function.

2-Thenoyltrifluoroacetone

326-91-0sc-251801
5 g
$36.00
1
(1)

TTFA is an inhibitor of mitochondrial complex II, which can affect overall mitochondrial function.

Piericidin A

2738-64-9sc-202287
2 mg
$285.00
24
(1)

Piericidin A is an antibiotic and has been shown to inhibit complex I of the mitochondrial respiratory chain.

Carboxine

5234-68-4sc-234286
250 mg
$21.00
1
(1)

Carboxin is an inhibitor of mitochondrial complex II.

Myxothiazol

76706-55-3sc-507550
1 mg
$145.00
(0)

Myxothiazol is another inhibitor of mitochondrial complex III.

Sodium azide

26628-22-8sc-208393
sc-208393B
sc-208393C
sc-208393D
sc-208393A
25 g
250 g
1 kg
2.5 kg
100 g
$42.00
$152.00
$385.00
$845.00
$88.00
8
(2)

Sodium azide is known to inhibit cytochrome c oxidase or complex IV.

Atovaquone

95233-18-4sc-217675
10 mg
$265.00
2
(0)

Atovaquone is an inhibitor of mitochondrial complex III.