hnRNP J activators belong to a specialized class of chemical compounds designed to modulate the activity of heterogeneous nuclear ribonucleoprotein J (hnRNP J), also known as polypyrimidine tract-binding protein-associated splicing factor (PSF). hnRNP J is a multifunctional protein involved in various aspects of RNA metabolism and cellular processes, including pre-mRNA splicing, RNA transport, transcriptional regulation, and DNA repair. These activators are carefully crafted to interact with hnRNP J, potentially influencing its diverse functions and impacting its role in orchestrating the intricate and dynamic processes related to RNA biology. The mechanisms through which hnRNP J activators exert their effects can be complex and multifaceted, often involving specific binding to hnRNP J's functional domains or modulating its interactions with RNA molecules and other cellular proteins.
Research on hnRNP J activators is vital for advancing our understanding of RNA biology and the intricate regulatory networks that govern gene expression and RNA processing. Scientists in this field primarily focus on elucidating the precise molecular mechanisms by which these compounds impact hnRNP J's function and their downstream effects on various cellular processes. hnRNP J is known to interact with a wide array of RNA molecules and other proteins, making it a central player in RNA-related cellular events. Consequently, understanding the role of hnRNP J activators contributes to our broader knowledge of gene regulation, splicing, and RNA metabolism, which are fundamental processes underlying cellular functions and differentiation. These activators serve as invaluable tools for researchers seeking to investigate the molecular basis of RNA biology and its implications in various physiological contexts, ultimately deepening our understanding of the complex world of RNA within the cell.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
DNA methyltransferase inhibitor; may modulate hnRNP J expression through epigenetic alterations. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Histone deacetylase inhibitor; could influence hnRNP J expression by altering chromatin accessibility. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
RNA polymerase II inhibitor; could impact hnRNP J as it affects mRNA synthesis. | ||||||
Oxaliplatin | 61825-94-3 | sc-202270 sc-202270A | 5 mg 25 mg | $110.00 $386.00 | 8 | |
DNA damage agent; might indirectly stimulate hnRNP J as part of the DNA damage response. | ||||||
Leptomycin B | 87081-35-4 | sc-358688 sc-358688A sc-358688B | 50 µg 500 µg 2.5 mg | $105.00 $408.00 $1224.00 | 35 | |
Nuclear export inhibitor; could potentially stabilize nuclear hnRNP J by preventing its export. | ||||||
Geldanamycin | 30562-34-6 | sc-200617B sc-200617C sc-200617 sc-200617A | 100 µg 500 µg 1 mg 5 mg | $38.00 $58.00 $102.00 $202.00 | 8 | |
HSP90 inhibitor; could indirectly affect hnRNP J stability or localization. | ||||||
ISRIB | 1597403-47-8 | sc-488404 | 10 mg | $300.00 | 1 | |
Affects the integrated stress response; might influence hnRNP J due to cellular response to stress. | ||||||
Ellipticine | 519-23-3 | sc-200878 sc-200878A | 10 mg 50 mg | $142.00 $558.00 | 4 | |
DNA intercalating agent; could indirectly influence hnRNP J through DNA damage response pathways. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
RNA polymerase II inhibitor; could affect hnRNP J due to its impact on mRNA synthesis. |