Date published: 2025-10-21

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hnRNP J Activators

hnRNP J activators belong to a specialized class of chemical compounds designed to modulate the activity of heterogeneous nuclear ribonucleoprotein J (hnRNP J), also known as polypyrimidine tract-binding protein-associated splicing factor (PSF). hnRNP J is a multifunctional protein involved in various aspects of RNA metabolism and cellular processes, including pre-mRNA splicing, RNA transport, transcriptional regulation, and DNA repair. These activators are carefully crafted to interact with hnRNP J, potentially influencing its diverse functions and impacting its role in orchestrating the intricate and dynamic processes related to RNA biology. The mechanisms through which hnRNP J activators exert their effects can be complex and multifaceted, often involving specific binding to hnRNP J's functional domains or modulating its interactions with RNA molecules and other cellular proteins.

Research on hnRNP J activators is vital for advancing our understanding of RNA biology and the intricate regulatory networks that govern gene expression and RNA processing. Scientists in this field primarily focus on elucidating the precise molecular mechanisms by which these compounds impact hnRNP J's function and their downstream effects on various cellular processes. hnRNP J is known to interact with a wide array of RNA molecules and other proteins, making it a central player in RNA-related cellular events. Consequently, understanding the role of hnRNP J activators contributes to our broader knowledge of gene regulation, splicing, and RNA metabolism, which are fundamental processes underlying cellular functions and differentiation. These activators serve as invaluable tools for researchers seeking to investigate the molecular basis of RNA biology and its implications in various physiological contexts, ultimately deepening our understanding of the complex world of RNA within the cell.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

DNA methyltransferase inhibitor; may modulate hnRNP J expression through epigenetic alterations.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

Histone deacetylase inhibitor; could influence hnRNP J expression by altering chromatin accessibility.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$260.00
$1029.00
26
(2)

RNA polymerase II inhibitor; could impact hnRNP J as it affects mRNA synthesis.

Oxaliplatin

61825-94-3sc-202270
sc-202270A
5 mg
25 mg
$110.00
$386.00
8
(1)

DNA damage agent; might indirectly stimulate hnRNP J as part of the DNA damage response.

Leptomycin B

87081-35-4sc-358688
sc-358688A
sc-358688B
50 µg
500 µg
2.5 mg
$105.00
$408.00
$1224.00
35
(2)

Nuclear export inhibitor; could potentially stabilize nuclear hnRNP J by preventing its export.

Geldanamycin

30562-34-6sc-200617B
sc-200617C
sc-200617
sc-200617A
100 µg
500 µg
1 mg
5 mg
$38.00
$58.00
$102.00
$202.00
8
(1)

HSP90 inhibitor; could indirectly affect hnRNP J stability or localization.

ISRIB

1597403-47-8sc-488404
10 mg
$300.00
1
(0)

Affects the integrated stress response; might influence hnRNP J due to cellular response to stress.

Ellipticine

519-23-3sc-200878
sc-200878A
10 mg
50 mg
$142.00
$558.00
4
(1)

DNA intercalating agent; could indirectly influence hnRNP J through DNA damage response pathways.

DRB

53-85-0sc-200581
sc-200581A
sc-200581B
sc-200581C
10 mg
50 mg
100 mg
250 mg
$42.00
$185.00
$310.00
$650.00
6
(1)

RNA polymerase II inhibitor; could affect hnRNP J due to its impact on mRNA synthesis.