Date published: 2025-12-5

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Histone Modification

Santa Cruz Biotechnology now offers a broad range of histone modification products for use in various applications. Histone modification products are essential tools in epigenetics research, as they help scientists study the post-translational modifications of histone proteins that regulate gene expression and chromatin structure. These modifications, including methylation, acetylation, phosphorylation, and ubiquitination, play critical roles in controlling access to DNA and thus influence numerous cellular processes such as transcription, replication, and repair. Researchers utilize histone modification products to investigate the dynamic changes in chromatin states and their impact on gene activity. These products are used to map histone modifications across the genome, analyze the enzymes responsible for adding or removing these marks, and understand how these modifications affect chromatin accessibility and gene regulation. By studying histone modifications, scientists gain insights into the mechanisms of cell differentiation, development, and the response to environmental signals. Additionally, histone modification products are pivotal in exploring the epigenetic basis of diseases, enabling the identification of novel targets. By providing a comprehensive selection of high-quality histone modification products, Santa Cruz Biotechnology supports advanced research in molecular biology, genetics, and epigenetics, empowering scientists to achieve precise and reproducible results. These products drive forward our understanding of gene regulation and the complex interplay between epigenetic modifications and cellular function. View detailed information on our available histone modification products by clicking on the product name.

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MRN-ATM Pathway Inhibitor, Mirin

299953-00-7sc-203144
10 mg
$138.00
4
(1)

MRN-ATM Pathway Inhibitor, Mirin, is a potent modulator of the MRN complex, which is essential for DNA damage response and repair. By selectively inhibiting the ATM kinase, Mirin disrupts the phosphorylation of histone proteins, leading to altered chromatin structure and dynamics. This interference affects the recruitment of repair factors, thereby influencing the kinetics of DNA repair pathways. Its unique interaction with the MRN complex highlights its role in epigenetic regulation.