hCG_1657980 Inhibitors
The class of chemicals referred to as hCG_1657980 Inhibitors encompasses a diverse range of compounds targeting key signaling pathways involved in the activation of hCG_1657980. These inhibitors act through various mechanisms, such as kinase inhibition, interference with upstream regulators, and modulation of crucial signaling cascades. Staurosporine, for instance, disrupts hCG_1657980 by acting as a potent ATP-competitive kinase inhibitor, inhibiting its phosphorylation activity. Wortmannin obstructs hCG_1657980 by irreversibly binding to PI3K, a crucial upstream modulator, thereby disrupting the pathway leading to hCG_1657980 activation.
PP2, U0126, LY294002, AG-490, Rapamycin, SB203580, SP600125, PD98059, JSH-23, and Curcumin act as selective inhibitors targeting specific signaling pathways associated with hCG_1657980. For example, SB203580 and SP600125 inhibit p38 and JNK, respectively, disrupting their respective pathways critical for hCG_1657980 activation. Curcumin, with its broad-spectrum interference, modulates multiple pathways, including NF-κB and MAPK, providing a comprehensive inhibition of hCG_1657980. This class of inhibitors, through their precise targeting of key cellular pathways, presents a valuable toolkit for studying the regulatory mechanisms and functional roles of hCG_1657980.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Staurosporine inhibits hCG_1657980 by acting as a potent ATP-competitive kinase inhibitor, disrupting its phosphorylation activity and impeding downstream signaling cascades. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin hinders hCG_1657980 by targeting phosphoinositide 3-kinase (PI3K), a crucial upstream modulator. By binding irreversibly to PI3K, it obstructs the pathway, thereby inhibiting hCG_1657980 activation. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 acts as a MEK inhibitor, curtailing the mitogen-activated protein kinase (MAPK) pathway. This interference blocks the downstream events leading to hCG_1657980 activation, hindering its functional role. | ||||||
JAK Inhibitor I | 457081-03-7 | sc-204021 sc-204021A | 500 µg 1 mg | $153.00 $332.00 | 59 | |
AG-490 is a JAK2 inhibitor that interferes with Janus kinase 2 signaling. By inhibiting this upstream regulator, AG-490 disrupts the pathway involved in hCG_1657980 activation, impeding its functional role. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin obstructs hCG_1657980 by targeting mTOR, a key component of the mTOR signaling pathway. This inhibition disrupts downstream events essential for the activation and function of hCG_1657980. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 acts as a p38 inhibitor, impeding the p38 mitogen-activated protein kinase pathway. By disrupting this signaling cascade, it interferes with the activation and function of hCG_1657980. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 inhibits hCG_1657980 by targeting c-Jun N-terminal kinase (JNK), a component of the MAPK pathway. Its interference disrupts the signaling cascade essential for the activation of hCG_1657980. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 hinders hCG_1657980 by targeting MEK1/2, preventing activation of the MAPK/ERK pathway. This interference disrupts downstream signaling, impeding the functional role of hCG_1657980. | ||||||
NFκB Activation Inhibitor II, JSH-23 | 749886-87-1 | sc-222061 sc-222061C sc-222061A sc-222061B | 5 mg 10 mg 50 mg 100 mg | $210.00 $252.00 $1740.00 $1964.00 | 34 | |
JSH-23 inhibits hCG_1657980 through NF-κB blockade. By disrupting the NF-κB signaling pathway, it interferes with downstream events critical for the activation and function of hCG_1657980. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin inhibits hCG_1657980 by modulating multiple signaling pathways, including NF-κB and MAPK. Its broad-spectrum interference disrupts the intricate network of pathways essential for hCG_1657980 activation. | ||||||