H2AL1 Activators are a specialized class of chemical compounds identified for their ability to specifically interact with and activate the H2AL1 protein. This protein is part of a larger family of proteins that play significant roles in a range of cellular and biological processes. The unique feature of H2AL1 Activators is their targeted action, wherein they bind to and activate the H2AL1 protein. This interaction is crucial for understanding the molecular mechanisms that govern various cellular functions. Structurally, H2AL1 Activators exhibit a wide range of molecular designs, reflecting the diversity in their chemical composition. This structural variety is essential for their functionality, as it impacts their binding affinity to the H2AL1 protein and their efficacy in activating it. The development of H2AL1 Activators often involves detailed structure-activity relationship studies, which emphasize the importance of certain molecular characteristics for effective interaction with the protein target. Such specificity in their interaction with H2AL1 highlights the sophisticated nature of these compounds in exploring and understanding protein functionalities within cellular systems.
At the molecular level, the interaction between H2AL1 Activators and the H2AL1 protein is a key area of interest in the fields of biochemistry and molecular biology. Typically, this interaction involves the activator molecule binding to a specific site on the protein, inducing a conformational change that leads to the protein's activation. The activation of H2AL1 can significantly impact a variety of cellular functions, underscoring the importance of these activators in modulating cellular biochemistry. The precision with which H2AL1 Activators target the H2AL1 protein is particularly intriguing for studies focused on protein-ligand interactions and the subsequent biological effects. Furthermore, the study of H2AL1 Activators is contributing to a broader understanding of how small molecules can influence protein function. This research is crucial for elucidating the complex mechanisms of protein activation and regulation within cellular contexts, offering insights into the intricate network of molecular interactions that dictate cellular dynamics. Understanding the interaction dynamics of H2AL1 Activators with their target protein provides vital information on the dynamic nature of protein function and the potential ways in which these functions can be modulated by specific molecular entities.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
It may inhibit histone deacetylase (HDAC), leading to an open chromatin state and potentially increasing expression of genes, such as H2AL1. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
As an HDAC inhibitor, it may relax chromatin structure and thereby potentially increase the transcription of certain genes including H2AL1. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
It is incorporated into DNA and can inhibit DNA methyltransferases, possibly leading to gene activation by hypomethylation, potentially affecting H2AL1. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Known to modulate sirtuin activity, which may affect histone acetylation and potentially the expression of genes such as H2AL1. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
May affect various signaling pathways and modulate histone modifications, potentially impacting H2AL1 expression. | ||||||
Betulinic Acid | 472-15-1 | sc-200132 sc-200132A | 25 mg 100 mg | $115.00 $337.00 | 3 | |
May inhibit topoisomerase, which can lead to DNA relaxation and potentially influence gene expression, including H2AL1. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Known to intercalate into DNA and potentially affect DNA methylation and histone modification, thereby possibly influencing H2AL1 expression. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Can modulate gene expression through retinoic acid receptors, which may indirectly affect chromatin structure and H2AL1 expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
A potent HDAC inhibitor that could increase histone acetylation, possibly leading to an upregulation of H2AL1 expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Affects DNA methylation and histone acetylation, potentially influencing the expression of genes like H2AL1. | ||||||