Date published: 2026-4-13

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H2-Abβ Inhibitors

H2-Abβ Inhibitors belong to a specialized chemical class known for their distinctive molecular structure and functional characteristics. At their core, these inhibitors are designed to target and modulate the activity of the H2-Abβ protein. The H2-Abβ protein, a crucial component of the immune system, plays a pivotal role in the presentation of antigens to T cells, thus initiating immune responses. The inhibitors act by selectively binding to specific sites on the H2-Abβ protein, disrupting its normal functioning and impeding its ability to facilitate antigen presentation effectively. This targeted interference at the molecular level underscores the precision and specificity of H2-Abβ inhibitors, distinguishing them as potent agents within the broader landscape of immunomodulatory compounds.

H2-Abβ inhibitors is characterized by intricately designed molecular scaffolds that facilitate optimal interactions with the target protein. Researchers have meticulously engineered these compounds to possess high affinity and selectivity for the H2-Abβ protein, ensuring minimal off-target effects. The development of H2-Abβ inhibitors represents a significant advancement in the field of molecular pharmacology, offering a nuanced approach to modulating immune responses.

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Items 1 to 10 of 11 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin can downregulate MHC class II expression by inhibiting the transactivator CIITA.

Chloroquine

54-05-7sc-507304
250 mg
$69.00
2
(0)

Chloroquine can elevate the pH of endosomes, potentially altering antigen processing for MHC class II molecules.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Quercetin can inhibit the activity of kinases involved in the signaling pathways that regulate MHC class II expression.

BAY 11-7082

19542-67-7sc-200615B
sc-200615
sc-200615A
5 mg
10 mg
50 mg
$62.00
$85.00
$356.00
155
(1)

BAY 11-7082 can inhibit NF-κB, a transcription factor that can regulate MHC class II expression.

Monensin A

17090-79-8sc-362032
sc-362032A
5 mg
25 mg
$155.00
$525.00
(1)

Monensin can disrupt endosomal compartments, potentially affecting antigen processing for MHC class II.

Wogonin, S. baicalensis

632-85-9sc-203313
10 mg
$200.00
8
(1)

Wogonin can inhibit the expression of co-stimulatory molecules potentially involved in MHC class II presentation.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

This compound can alter the immune response, potentially affecting MHC class II-dependent antigen presentation.

Apigenin

520-36-5sc-3529
sc-3529A
sc-3529B
sc-3529C
sc-3529D
sc-3529E
sc-3529F
5 mg
100 mg
1 g
5 g
25 g
100 g
1 kg
$33.00
$214.00
$734.00
$1151.00
$2348.00
$3127.00
$5208.00
22
(1)

Apigenin can influence various signaling pathways and may alter MHC class II expression.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$60.00
$265.00
$1000.00
163
(3)

MG132 can inhibit the proteasome, potentially affecting the peptide supply for MHC class II loading.

Withaferin A

5119-48-2sc-200381
sc-200381A
sc-200381B
sc-200381C
1 mg
10 mg
100 mg
1 g
$130.00
$583.00
$4172.00
$20506.00
20
(1)

Withaferin A can modulate immune system responses, possibly influencing MHC class II function.