H2-Abβ Inhibitors belong to a specialized chemical class known for their distinctive molecular structure and functional characteristics. At their core, these inhibitors are designed to target and modulate the activity of the H2-Abβ protein. The H2-Abβ protein, a crucial component of the immune system, plays a pivotal role in the presentation of antigens to T cells, thus initiating immune responses. The inhibitors act by selectively binding to specific sites on the H2-Abβ protein, disrupting its normal functioning and impeding its ability to facilitate antigen presentation effectively. This targeted interference at the molecular level underscores the precision and specificity of H2-Abβ inhibitors, distinguishing them as potent agents within the broader landscape of immunomodulatory compounds.
H2-Abβ inhibitors is characterized by intricately designed molecular scaffolds that facilitate optimal interactions with the target protein. Researchers have meticulously engineered these compounds to possess high affinity and selectivity for the H2-Abβ protein, ensuring minimal off-target effects. The development of H2-Abβ inhibitors represents a significant advancement in the field of molecular pharmacology, offering a nuanced approach to modulating immune responses.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin can downregulate MHC class II expression by inhibiting the transactivator CIITA. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $69.00 | 2 | |
Chloroquine can elevate the pH of endosomes, potentially altering antigen processing for MHC class II molecules. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin can inhibit the activity of kinases involved in the signaling pathways that regulate MHC class II expression. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $62.00 $85.00 $356.00 | 155 | |
BAY 11-7082 can inhibit NF-κB, a transcription factor that can regulate MHC class II expression. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $155.00 $525.00 | ||
Monensin can disrupt endosomal compartments, potentially affecting antigen processing for MHC class II. | ||||||
Wogonin, S. baicalensis | 632-85-9 | sc-203313 | 10 mg | $200.00 | 8 | |
Wogonin can inhibit the expression of co-stimulatory molecules potentially involved in MHC class II presentation. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
This compound can alter the immune response, potentially affecting MHC class II-dependent antigen presentation. | ||||||
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $33.00 $214.00 $734.00 $1151.00 $2348.00 $3127.00 $5208.00 | 22 | |
Apigenin can influence various signaling pathways and may alter MHC class II expression. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
MG132 can inhibit the proteasome, potentially affecting the peptide supply for MHC class II loading. | ||||||
Withaferin A | 5119-48-2 | sc-200381 sc-200381A sc-200381B sc-200381C | 1 mg 10 mg 100 mg 1 g | $130.00 $583.00 $4172.00 $20506.00 | 20 | |
Withaferin A can modulate immune system responses, possibly influencing MHC class II function. | ||||||