The Gm9839 Inhibitors chemical class includes a variety of compounds that interact with and potentially modulate the activity of proteins similar to those encoded by the gene Gm9839. This class is characterized by a range of inhibitors that target key signaling molecules and pathways within the cell, each with a unique mechanism of action that can indirectly influence the function of Gm9839 proteins.
Starting with Alpelisib and extending through compounds like Buparlisib, Copanlisib, and Duvelisib, this class primarily targets the phosphoinositide 3-kinase (PI3K) pathway. The PI3K pathway is crucial in regulating cell growth, survival, and proliferation. By modulating this pathway, these inhibitors can significantly impact the activity of proteins involved in these processes, potentially including those related to Gm9839. Idelalisib, another PI3K inhibitor, reinforces this class's focus on disrupting critical signaling pathways that regulate a wide range of cellular functions.
The class also includes Ipatasertib and Uprosertib, which target the AKT kinase, another key player in cell survival and growth signaling pathways. The modulation of AKT activity by these inhibitors can have profound effects on cellular processes that regulate protein function and activity. Omipalisib and Gedatolisib, both targeting PI3K and mTOR, illustrate the class's capacity to affect multiple key signaling pathways simultaneously, offering a broader scope of potential impact on protein functions.
Taselisib, Pictilisib, and Zandelisib continue to emphasize the class's focus on the PI3K pathway, showcasing the range of compounds capable of modulating this critical signaling axis. Each of these inhibitors has the potential to alter the activity of proteins involved in cell signaling and growth, providing insights into the modulation of proteins similar to those encoded by Gm9839.
Collectively, the Gm9839 Inhibitors represent a diverse array of compounds capable of interacting with various cellular mechanisms and pathways. These interactions, achieved through targeting critical signaling molecules like PI3K and AKT, offer valuable insights into how such compounds could influence the function of proteins akin to those encoded by Gm9839. This class demonstrates the intricate nature of cellular signaling and its profound impact on protein activity and function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
BYL719 | 1217486-61-7 | sc-391001 sc-391001A sc-391001B sc-391001C sc-391001D sc-391001E | 5 mg 10 mg 50 mg 100 mg 500 mg 1 g | $383.00 $585.00 $740.00 $1169.00 $4902.00 $9186.00 | 2 | |
A PI3K inhibitor, Alpelisib can modulate cell survival and growth pathways, affecting protein activity. | ||||||
BKM120 | 944396-07-0 | sc-364437 sc-364437A sc-364437B sc-364437C | 5 mg 10 mg 25 mg 50 mg | $173.00 $230.00 $275.00 $332.00 | 9 | |
Targets PI3K, Buparlisib can influence cell signaling and protein functions related to Gm9839. | ||||||
BAY 80-6946 | 1032568-63-0 | sc-503264 | 5 mg | $551.00 | ||
Inhibits PI3K, Copanlisib can affect cell growth and survival pathways, impacting protein activity. | ||||||
IPI 145 | 1201438-56-3 | sc-488318 | 5 mg | $311.00 | ||
Targets PI3K, Duvelisib can modulate cell signaling, potentially influencing protein function. | ||||||
CAL-101 | 870281-82-6 | sc-364453 | 10 mg | $189.00 | 4 | |
A PI3K inhibitor, Idelalisib can disrupt signaling pathways, affecting protein functions. | ||||||
(2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone | sc-501166 | 5 mg | $540.00 | |||
Targets AKT, Ipatasertib can modulate cell survival and growth pathways, influencing protein activity. | ||||||
GDC-0941 | 957054-30-7 | sc-364498 sc-364498A | 5 mg 10 mg | $184.00 $195.00 | 2 | |
Inhibits PI3K and mTOR, Omipalisib can affect key cell signaling pathways, impacting protein function. | ||||||