Date published: 2025-10-30

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Gm1862 Inhibitors

The chemical class known as Gm1862 Inhibitors comprises a unique group of compounds formulated to specifically target and inhibit the activity of the gene product encoded by Gm1862. This gene, identified through comprehensive genetic sequencing and analysis, holds a significant position in various cellular pathways, and its precise function can be context-dependent, varying with different cellular environments and stimuli. The inhibitors in this class are designed to bind selectively to the proteins or enzymes that are expressed as a result of Gm1862's activation. This binding is a key feature of these inhibitors, as it directly influences the biochemical pathways in which the Gm1862 gene product is involved. By modulating the activity of this gene product, these inhibitors exert their effects on the associated cellular processes.

Developing inhibitors for Gm1862 involves an interdisciplinary approach, combining insights from molecular biology, chemistry, and bioinformatics. The initial phase of this development is centered around gaining a comprehensive understanding of the structure and functional dynamics of the Gm1862 gene product. Techniques such as X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and computer-aided molecular design play pivotal roles in this process. Such advanced techniques enable researchers to discern the intricate details of the target molecule, facilitating the rational design of inhibitors that are both potent and highly specific. The molecular structure of these inhibitors is typically optimized to ensure effective penetration into cellular compartments and stable interaction with their target. This optimization often involves fine-tuning the molecular architecture to foster strong hydrogen bonds, hydrophobic interactions, and van der Waals forces with the target molecule. The efficacy of these inhibitors is rigorously tested through various biochemical assays, which are crucial in determining their inhibitory potency and specificity. These assays provide valuable insights into the behavior of the inhibitors in controlled experimental conditions, laying the groundwork for further understanding of their mechanism of action and interaction dynamics.

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Fluorouracil

51-21-8sc-29060
sc-29060A
1 g
5 g
$36.00
$149.00
11
(1)

A uracil analog that can be incorporated into RNA and disrupt RNA processing and function.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$40.00
$82.00
$256.00
127
(5)

Inhibits eukaryotic protein synthesis by interfering with the translocation step in protein elongation.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

Intercalates into DNA and prevents the transcription elongation by RNA polymerase.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$260.00
$1029.00
26
(2)

Specifically inhibits RNA polymerase II in eukaryotes, affecting mRNA production.

Etoposide (VP-16)

33419-42-0sc-3512B
sc-3512
sc-3512A
10 mg
100 mg
500 mg
$32.00
$170.00
$385.00
63
(1)

Inhibits DNA topoisomerase II, leading to DNA damage and affecting gene transcription.

Doxorubicin

23214-92-8sc-280681
sc-280681A
1 mg
5 mg
$173.00
$418.00
43
(3)

Interacts with DNA by intercalation and inhibition of macromolecular biosynthesis, affecting gene expression.

Bleomycin

11056-06-7sc-507293
5 mg
$270.00
5
(0)

Causes DNA strand breaks and inhibits DNA synthesis, potentially affecting gene expression.

Bortezomib

179324-69-7sc-217785
sc-217785A
2.5 mg
25 mg
$132.00
$1064.00
115
(2)

Inhibits the 26S proteasome, affecting protein turnover and potentially downstream gene expression.

Methotrexate

59-05-2sc-3507
sc-3507A
100 mg
500 mg
$92.00
$209.00
33
(5)

Inhibits dihydrofolate reductase, affecting nucleotide synthesis and therefore gene expression.