GHR activators belong to a specialized class of chemical compounds designed to modulate the activity of the Growth Hormone Receptor (GHR), also known as the Growth Hormone Binding Protein (GHBP) or the somatotropin receptor. The GHR is a transmembrane receptor that plays a pivotal role in mediating the effects of growth hormone (GH) in various tissues and cells throughout the body. Growth hormone, produced by the anterior pituitary gland, is essential for regulating growth, development, and metabolism. Upon binding to GHR, growth hormone initiates a cascade of signaling events, ultimately leading to the activation of downstream pathways involved in cell growth, proliferation, and differentiation.
GHR activators are meticulously designed compounds engineered to interact with the GHR receptor, modulating its activity in a way that influences cellular responses to growth hormone. These compounds are fundamental tools for researchers investigating the molecular mechanisms of growth hormone signaling and its impact on cellular processes. By manipulating GHR activity, scientists aim to uncover the intricate regulatory pathways that govern growth hormone-mediated effects, unraveling the complexity of growth and development at the cellular level. GHR activators are essential in advancing our understanding of endocrine signaling and its relevance to growth and metabolism, contributing to the broader field of molecular biology and physiology.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
β-Estradiol, a form of estrogen, may enhance GHR expression by interacting with estrogen receptors, which can modulate GH signaling pathways. | ||||||
Ob (hBA-147) | sc-4912 | 1000 µg | $253.00 | 1 | ||
Ob (hBA-147), involved in energy regulation, might influence GHR expression through its role in the regulation of growth hormone. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $153.00 $1224.00 $12239.00 | 82 | |
Insulin can modulate GHR expression, possibly through its role in growth and metabolic regulation. | ||||||
L-Thyroxine, free acid | 51-48-9 | sc-207813 sc-207813A | 100 mg 500 mg | $34.00 $73.00 | 2 | |
L-Thyroxine, a thyroid hormone, potentially increases GHR expression, contributing to its role in growth and metabolic processes. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid may affect GHR expression through its involvement in cellular growth and differentiation processes. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone might influence GHR expression, possibly through glucocorticoid receptor interactions affecting growth and metabolism. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Cholecalciferol may modulate GHR expression, potentially through its role in cellular growth and bone metabolism. | ||||||
Folic Acid | 59-30-3 | sc-204758 | 10 g | $72.00 | 2 | |
Folic acid, essential for cell growth, might play a role in GHR expression, particularly in cellular development and metabolism. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc, as Zinc sulfate, could influence GHR expression, possibly through its role in growth and metabolic regulation. | ||||||