Date published: 2025-12-15

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GHR Activators

GHR activators belong to a specialized class of chemical compounds designed to modulate the activity of the Growth Hormone Receptor (GHR), also known as the Growth Hormone Binding Protein (GHBP) or the somatotropin receptor. The GHR is a transmembrane receptor that plays a pivotal role in mediating the effects of growth hormone (GH) in various tissues and cells throughout the body. Growth hormone, produced by the anterior pituitary gland, is essential for regulating growth, development, and metabolism. Upon binding to GHR, growth hormone initiates a cascade of signaling events, ultimately leading to the activation of downstream pathways involved in cell growth, proliferation, and differentiation.

GHR activators are meticulously designed compounds engineered to interact with the GHR receptor, modulating its activity in a way that influences cellular responses to growth hormone. These compounds are fundamental tools for researchers investigating the molecular mechanisms of growth hormone signaling and its impact on cellular processes. By manipulating GHR activity, scientists aim to uncover the intricate regulatory pathways that govern growth hormone-mediated effects, unraveling the complexity of growth and development at the cellular level. GHR activators are essential in advancing our understanding of endocrine signaling and its relevance to growth and metabolism, contributing to the broader field of molecular biology and physiology.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

β-Estradiol

50-28-2sc-204431
sc-204431A
500 mg
5 g
$62.00
$178.00
8
(1)

β-Estradiol, a form of estrogen, may enhance GHR expression by interacting with estrogen receptors, which can modulate GH signaling pathways.

Ob (hBA-147)

sc-4912
1000 µg
$253.00
1
(0)

Ob (hBA-147), involved in energy regulation, might influence GHR expression through its role in the regulation of growth hormone.

Insulin

11061-68-0sc-29062
sc-29062A
sc-29062B
100 mg
1 g
10 g
$153.00
$1224.00
$12239.00
82
(1)

Insulin can modulate GHR expression, possibly through its role in growth and metabolic regulation.

L-Thyroxine, free acid

51-48-9sc-207813
sc-207813A
100 mg
500 mg
$34.00
$73.00
2
(0)

L-Thyroxine, a thyroid hormone, potentially increases GHR expression, contributing to its role in growth and metabolic processes.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Retinoic acid may affect GHR expression through its involvement in cellular growth and differentiation processes.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$76.00
$82.00
$367.00
36
(1)

Dexamethasone might influence GHR expression, possibly through glucocorticoid receptor interactions affecting growth and metabolism.

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$70.00
$160.00
$290.00
2
(1)

Cholecalciferol may modulate GHR expression, potentially through its role in cellular growth and bone metabolism.

Folic Acid

59-30-3sc-204758
10 g
$72.00
2
(1)

Folic acid, essential for cell growth, might play a role in GHR expression, particularly in cellular development and metabolism.

Zinc

7440-66-6sc-213177
100 g
$47.00
(0)

Zinc, as Zinc sulfate, could influence GHR expression, possibly through its role in growth and metabolic regulation.