Date published: 2026-5-6

1-800-457-3801

SCBT Portrait Logo
Seach Input

General Crosslinkers

Santa Cruz Biotechnology now offers a broad range of crosslinkers for use in various applications. Crosslinkers are versatile chemical agents that can form covalent bonds between different molecules, thus linking them together. These compounds are crucial in scientific research for stabilizing the structure of proteins, nucleic acids, and other biomolecules, allowing for more accurate studies of their functions and interactions. By creating crosslinked networks, researchers can investigate the three-dimensional structure of macromolecules, study the dynamics of complex biological systems, and enhance the durability and functionality of biomaterials. In material science, crosslinkers are used to develop polymers with improved mechanical properties, such as increased strength and resistance to solvents and heat. Additionally, they play a vital role in developing and optimizing new materials, adhesives, coatings, and composites. The ability of crosslinkers to create strong, stable bonds has also been utilized in various biochemical techniques, such as immunoprecipitation, chromatography, and mass spectrometry, where they help in isolating and identifying specific molecules from complex mixtures. Santa Cruz Biotechnology provides a wide selection of crosslinkers, each with unique properties tailored for specific research needs, ensuring researchers have the tools necessary for their studies. View detailed information on our available crosslinkers by clicking on the product name.

Items 151 to 160 of 343 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

2-[N2-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-N6-(6 -biotinamidocaproyl)-L-lysinyl]ethyl 2-Carboxyethyl Disulfide

sc-213714
1 mg
$330.00
(0)

2-[N2-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-N6-(6-biotinamidocaproyl)-L-lysinyl]ethyl 2-Carboxyethyl Disulfide serves as a versatile crosslinker, characterized by its ability to form stable covalent bonds through thiol-disulfide exchange reactions. The azido group enables bioorthogonal click chemistry, facilitating selective conjugation with various biomolecules. Its unique structure promotes specific interactions with target sites, enhancing the efficiency of crosslinking in complex biochemical environments.

2-[N2-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-N6-(6-biotinamidocaproyl)-L-lysinyl]ethyl Methanethiosulfonate

1356383-18-0sc-213715
1 mg
$396.00
(0)

2-[N2-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-N6-(6-biotinamidocaproyl)-L-lysinyl]ethyl Methanethiosulfonate acts as an advanced crosslinker, characterized by its methanethiosulfonate group that promotes thiol-reactive crosslinking. The azido moiety allows for bioorthogonal reactions, enabling precise targeting in diverse biochemical contexts. Its unique structure supports the formation of stable linkages while maintaining the potential for dynamic interactions, making it suitable for complex molecular assemblies.

2-{N2-[N6-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-6 -aminocaproyl]-N6-(6-biotinamidocaproyl)-L -lysinylamido}] Ethyl 2-Carboxyethyl Disulfide

sc-213718
1 mg
$360.00
(0)

2-{N2-[N6-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-6-aminocaproyl]-N6-(6-biotinamidocaproyl)-L-lysinylamido}] Ethyl 2-Carboxyethyl Disulfide serves as a sophisticated crosslinker, featuring multiple reactive sites that facilitate robust covalent bonding. Its unique azido and biotin functionalities enable selective conjugation to biomolecules, enhancing specificity in complex systems. The disulfide linkage provides dynamic stability, allowing for reversible interactions that can be finely tuned in various environments.

6-(N-Trifluoroacetyl)aminocaproic Acid

sc-217289
50 mg
$300.00
(0)

6-(N-Trifluoroacetyl)aminocaproic Acid serves as a versatile crosslinker, characterized by its ability to form stable covalent bonds through its reactive trifluoroacetyl group. This compound facilitates unique molecular interactions, enhancing the structural integrity of polymers. Its distinct reaction kinetics allow for controlled crosslinking under mild conditions, promoting tailored material properties. The presence of the trifluoroacetyl moiety also contributes to increased hydrophobicity, influencing solubility and compatibility with various substrates.

6-(N-Trifluoroacetyl)aminocaproic Acid N-Succinimidyl Ester

sc-217290
50 mg
$320.00
(0)

6-(N-Trifluoroacetyl)aminocaproic Acid N-Succinimidyl Ester acts as an effective crosslinker, distinguished by its ability to engage in selective amide bond formation. The succinimidyl ester group enhances reactivity, enabling rapid conjugation with nucleophiles. This compound exhibits unique solvation dynamics, which can modulate the crosslinking density and network formation. Its trifluoroacetyl component introduces steric hindrance, influencing the spatial arrangement of linked entities and enhancing material stability.

Bis-(2-methanethiosulfonatoethyl)dimethylammonium Chloride

sc-217766
5 mg
$360.00
(0)

Bis-(2-methanethiosulfonatoethyl)dimethylammonium Chloride functions as an effective crosslinker, distinguished by its ability to form covalent bonds through thiol-disulfide exchange reactions. This compound exhibits a unique dual reactivity profile, enabling it to create robust networks in various environments. Its zwitterionic nature enhances compatibility with diverse substrates, while its specific molecular interactions facilitate controlled crosslinking dynamics, optimizing material properties.

Decaoxadotriacontadioic Acid Bis(N-Hydroxysuccinimide) Ester

sc-218093
5 mg
$430.00
(0)

Decaoxadotriacontadioic Acid Bis(N-Hydroxysuccinimide) Ester serves as an effective crosslinker due to its multifunctional nature, enabling the formation of stable covalent bonds through its reactive ester groups. The compound's extended carbon chain enhances flexibility, allowing for tailored network structures. Its ability to facilitate diverse molecular interactions, including electrostatic and van der Waals forces, contributes to the formation of robust polymeric matrices, optimizing mechanical properties and durability.

N-(2-Maleimidoethyl)-6-t-Boc-aminohexanamide

sc-218917
25 mg
$330.00
(0)

N-(2-Maleimidoethyl)-6-t-Boc-aminohexanamide functions as a versatile crosslinker, characterized by its maleimide group that engages in selective reactions with thiols, yielding durable thioether linkages. The presence of the t-Boc protecting group enhances stability and solubility, allowing for controlled release of the active maleimide. This compound's unique reactivity profile supports the formation of intricate polymer networks, optimizing mechanical properties and structural integrity in diverse applications.

N-[S-(2-Pyridylthioethyl)-t-Boc-aminooxyacetamide

sc-219003
10 mg
$300.00
(0)

N-[S-(2-Pyridylthioethyl)-t-Boc-aminooxyacetamide serves as an innovative crosslinker, featuring a pyridylthioethyl moiety that promotes selective interactions with target substrates. Its aminooxyacetamide functionality enables efficient formation of oxime bonds, facilitating rapid crosslinking under mild conditions. The compound's unique architecture allows for enhanced solubility and reactivity, leading to tailored network structures that improve mechanical properties and stability in diverse applications.

N-Succinimidyl 6-(3-Maleimidopropionamido) Hexanoate

sc-219226
10 mg
$300.00
(0)

N-Succinimidyl 6-(3-Maleimidopropionamido) Hexanoate is a specialized crosslinker featuring a reactive succinimidyl group that enables robust amine coupling. The maleimide component facilitates specific thiol interactions, allowing for precise crosslinking in complex systems. Its hexanoate chain provides a balance of rigidity and flexibility, enhancing molecular mobility. This unique structure promotes efficient reaction kinetics and stability, making it suitable for diverse applications in material science and bioconjugation.