GCNT7 Activators
GCNT7, also known as glucosaminyl (N-acetyl) transferase 7, is an enzyme that belongs to the family of glycosyltransferases, specifically the glucosaminyltransferase subfamily. Enzymes in this family are involved in the biosynthesis of glycoproteins by adding carbohydrate moieties to specific protein residues, which is a critical post-translational modification that affects protein folding, stability, and function.
As a glycosyltransferase, GCNT7 catalyzes the transfer of N-acetylglucosamine (GlcNAc) to serine or threonine residues in proteins. This process is part of the O-glycosylation pathway, which is essential for the proper function of many proteins. The specific substrates and biological functions of GCNT7, however, have not been as thoroughly researched or understood as those of some other members of the glycosyltransferase family.The expression of GCNT7 has been detected in various tissues, suggesting a potential role in numerous physiological processes. The enzymes in this family are known to impact cellular signaling, molecular trafficking, cell-cell interactions, and the immune response. Abnormal glycosylation patterns have been implicated in a range of diseases, including cancer, infectious diseases, and genetic disorders, which highlights the importance of enzymes like GCNT7 in maintaining cellular health and homeostasis.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylyl cyclase, increasing cAMP levels. Elevated cAMP may enhance GCNT7 expression by activating cAMP-dependent pathways. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $27.00 $37.00 | 5 | |
Isoproterenol, a beta-adrenergic agonist, elevates cAMP, which in turn could upregulate GCNT7 via cAMP-responsive elements in its promoter region. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Ionomycin is a calcium ionophore that raises intracellular Ca2+ levels, potentially enhancing GCNT7 expression through Ca2+-dependent signaling. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C (PKC), which may lead to increased GCNT7 expression through PKC-mediated signaling pathways. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
A23187 acts as a calcium ionophore, which can indirectly increase GCNT7 activity by modulating calcium-dependent protein kinases. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid modulates gene expression through retinoic acid receptors, which could enhance GCNT7 expression as part of a gene regulatory network. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $45.00 $130.00 $480.00 $4450.00 | 74 | |
Dibutyryl-cAMP, a cAMP analog, may enhance GCNT7 activity by mimicking the action of cAMP and activating cAMP-dependent signaling pathways. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG inhibits various protein kinases, potentially leading to altered signaling cascades that upregulate GCNT7 expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor that may influence GCNT7 expression by altering downstream AKT signaling, which is implicated in gene regulation. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 inhibits MEK, which could result in a compensatory increase in GCNT7 expression due to disruption of the MAPK/ERK signaling pathway. | ||||||