FLJ44815 inhibitors are small molecules or compounds that specifically target the FLJ44815 protein, a component involved in various cellular signaling and regulatory pathways. The inhibition of FLJ44815 can modulate biochemical activities such as protein-protein interactions or enzymatic functions, depending on the nature of the protein itself. FLJ44815 is believed to play a role in the transcriptional regulation of gene expression, which may involve the recruitment of cofactors or the modification of chromatin states. Inhibitors targeting FLJ44815 aim to disrupt its activity, thereby affecting downstream signaling pathways that are controlled or influenced by this protein. The mechanism of inhibition often involves binding to the active site or an allosteric region of FLJ44815, preventing it from interacting with other molecular targets.
Structurally, FLJ44815 inhibitors are typically characterized by a high degree of specificity, with the design of these molecules often based on structural studies of the target protein. This can involve X-ray crystallography or molecular docking studies that elucidate the binding pocket and key residues essential for interaction. Additionally, the chemical scaffolds used in these inhibitors may feature modifications that enhance binding affinity, selectivity, and metabolic stability. FLJ44815 inhibitors often undergo rigorous in vitro testing to assess their ability to block the protein's function, followed by further optimization to enhance potency and reduce off-target effects. The chemical diversity of these inhibitors allows for exploration of different binding modes and interactions, contributing to a better understanding of FLJ44815's role in cellular processes.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
PI3K inhibitor that can block downstream Akt signaling, possibly affecting FLJ44815 if it is regulated by PI3K signaling. | ||||||
Trametinib | 871700-17-3 | sc-364639 sc-364639A sc-364639B | 5 mg 10 mg 1 g | $112.00 $163.00 $928.00 | 19 | |
MEK inhibitor that can disrupt the MAPK/ERK pathway, potentially altering the function of FLJ44815 if it is part of this pathway. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $47.00 $145.00 | 51 | |
Src family kinase inhibitor that can interfere with cell migration and angiogenesis, possibly impacting FLJ44815 if it is associated with these processes. | ||||||
ABT-199 | 1257044-40-8 | sc-472284 sc-472284A sc-472284B sc-472284C sc-472284D | 1 mg 5 mg 10 mg 100 mg 3 g | $116.00 $330.00 $510.00 $816.00 $1632.00 | 10 | |
Bcl-2 inhibitor that can induce apoptosis, potentially affecting FLJ44815 if it plays a role in the apoptotic signaling pathway. | ||||||
Cobimetinib | 934660-93-2 | sc-507421 | 5 mg | $270.00 | ||
MEK inhibitor that can halt cell cycle progression, potentially affecting FLJ44815 if it is involved in cell cycle control. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor that can modulate stress responses and apoptosis, potentially affecting FLJ44815 if it is part of these responses. | ||||||
Carfilzomib | 868540-17-4 | sc-396755 | 5 mg | $40.00 | ||
Proteasome inhibitor that can prevent protein degradation, potentially affecting the stability of FLJ44815. | ||||||
Lenalidomide | 191732-72-6 | sc-218656 sc-218656A sc-218656B | 10 mg 100 mg 1 g | $49.00 $367.00 $2030.00 | 18 | |
Modulates the ubiquitin-proteasome system, potentially affecting the turnover of FLJ44815 if its degradation is ubiquitin-dependent. | ||||||
Tozasertib | 639089-54-6 | sc-358750 sc-358750A | 25 mg 50 mg | $61.00 $85.00 | 4 | |
Aurora kinase inhibitor that can disrupt cell division, potentially impacting FLJ44815 if it has a role in mitosis. | ||||||
Olaparib | 763113-22-0 | sc-302017 sc-302017A sc-302017B | 250 mg 500 mg 1 g | $206.00 $299.00 $485.00 | 10 | |
PARP inhibitor that can affect DNA repair mechanisms, potentially impacting FLJ44815 if it is involved in DNA damage response. | ||||||