FGFR1OP2 Inhibitors constitute a class of chemical compounds meticulously designed to interact with and modulate the activity of the FGFR1OP2 protein. FGFR1OP2, or Fibroblast Growth Factor Receptor 1 Oncogene Partner 2, is a protein involved in various cellular processes, particularly those linked to fibroblast growth factor receptors (FGFRs). The exact functions and molecular interactions of FGFR1OP2 are ongoing subjects of research, but it is recognized for its potential role in regulating FGFR signaling and associated cellular responses. Inhibitors developed for FGFR1OP2 are carefully engineered to interfere with or regulate its activity, potentially influencing the cellular processes in which it plays a role.
The mechanism of action for FGFR1OP2 inhibitors primarily involves their binding to the FGFR1OP2 protein, targeting its domains or interaction sites crucial for mediating FGFR signaling. These interactions enable the inhibitors to disrupt or modulate the function of FGFR1OP2, potentially affecting the transduction of signals initiated by FGFRs and their downstream cellular effects. Researchers rely on FGFR1OP2 inhibitors as crucial tools to unravel the complexities of cell signaling processes, particularly those involving FGFRs, and to gain deeper insights into the specific roles played by FGFR1OP2 in these cellular activities. By inhibiting FGFR1OP2, scientists aim to contribute to a more profound understanding of the molecular mechanisms governing cellular signaling, ultimately advancing the field of cell biology and signal transduction.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Erdafitinib | 1346242-81-6 | sc-507388 | 10 mg | $138.00 | ||
A pan-FGFR inhibitor, erdafitinib binds and inhibits the enzymatic activities of FGFRs, which may result in the inhibition of FGFR-related signal transduction pathways and, so, the inhibition of tumor cell proliferation and tumor growth. | ||||||
BGJ398 | 872511-34-7 | sc-364430 sc-364430A sc-364430B sc-364430C | 5 mg 10 mg 50 mg 100 mg | $216.00 $252.00 $594.00 $1009.00 | 4 | |
Highly selective for FGFR1-3, infigratinib binds and inhibits FGFRs, leading to the inhibition of FGFR-mediated signal transduction pathways and tumor cell proliferation. | ||||||
AZD4547 | 1035270-39-3 | sc-364421 sc-364421A | 5 mg 10 mg | $198.00 $309.00 | 6 | |
Selective for FGFR1-3, AZD4547 binds and inhibits these receptors, disrupting FGFR signaling and leading to the suppression of tumor growth. | ||||||
Debio-1347 | 1265229-25-1 | sc-507386 | 10 mg | $324.00 | ||
Targeting FGFR1, FGFR2, and FGFR3, Debio 1347 binds to and inhibits these receptors, leading to the suppression of FGFR signaling and tumor growth. | ||||||