FAM22D Activators
FAM22D activators are a category of chemical compounds that engage with the FAM22D protein, a member of the human gene family with unclear but potentially significant biological roles. These activators are designed to modulate the activity of the FAM22D protein, which may be involved in various cellular processes. The exact biological function of FAM22D remains to be thoroughly defined, but it is believed that it could play a role in the regulation of cellular functions that are critical for maintaining cellular homeostasis. The chemical structure of FAM22D activators can vary widely, with each activator having unique molecular features that enable it to interact specifically with the FAM22D protein. Such interactions typically involve the binding of the activator molecule to a specific region of the FAM22D protein, which in turn can affect the protein's conformation and modulate its activity within the cell.
The study of FAM22D activators involves an intricate understanding of biochemistry and molecular biology, as the interactions between these small molecules and the protein can be quite complex. The binding affinity and specificity of these chemical activators are of particular interest, as they dictate the efficiency and selectivity with which these compounds can modulate the FAM22D protein's function. In a broader context, the FAM22D protein is just one example within the vast landscape of human proteins that can be targeted by specific activators. Research into the mechanisms through which FAM22D activators exert their effects on the protein can provide insights into the fundamental principles of protein regulation. By understanding how these activators work at a molecular level, scientists can elucidate the role that the FAM22D protein plays within cells and how it interacts with other cellular components in the complex network of biological pathways.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Ionomycin is a calcium ionophore that increases intracellular calcium concentrations. By raising calcium levels, it can activate calcium-dependent kinases and phosphatases, which might lead to the post-translational modification and activation of FAM22D. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C (PKC), which can phosphorylate various substrates. Through PKC activation, PMA may enhance the phosphorylation state and activity of FAM22D if it is a substrate of PKC or involved in PKC-regulated pathways. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $153.00 $1224.00 $12239.00 | 82 | |
Insulin triggers the PI3K/Akt signaling pathway, which leads to a range of cellular responses. Activation of this pathway can enhance the activity of FAM22D if it plays a role in metabolic pathways or has phosphorylation sites targeted by Akt or downstream kinases. | ||||||
Bradykinin | 58-82-2 | sc-507311 | 5 mg | $110.00 | ||
Bradykinin binds to its receptor and activates PLC, which can increase intracellular calcium and activate PKC. The downstream effects of this signaling cascade can lead to the phosphorylation and potential activation of FAM22D. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $162.00 $316.00 $559.00 $889.00 $1693.00 | 7 | |
S1P binds to its G-protein coupled receptors and can activate several downstream signaling pathways, including those involving PI3K/Akt and MAPK. This broad activation can enhance the functional activity of FAM22D if it is associated with these signaling pathways. | ||||||
8-Bromo-cGMP | 51116-01-9 | sc-200316 sc-200316A | 10 mg 50 mg | $102.00 $347.00 | 7 | |
8-Br-cGMP is a cell-permeable analog of cGMP which activates PKG. Activation of PKG can lead to phosphorylation of target proteins, potentially enhancing the activity of FAM22D, especially if it is influenced by cGMP-dependent signaling. | ||||||
Histamine, free base | 51-45-6 | sc-204000 sc-204000A sc-204000B | 1 g 5 g 25 g | $92.00 $277.00 $969.00 | 7 | |
Histamine binds to its receptors and can activate several intracellular signaling cascades, such as those involving cAMP and calcium signaling. These pathways can lead to the activation of FAM22D if it is involved in these signaling processes. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $56.00 $156.00 $270.00 $665.00 | 37 | |
PGE2 interacts with its G-protein coupled receptors, which can lead to the activation of adenylate cyclase and subsequent increase in cAMP. Elevated cAMP can activate PKA and potentially enhance the activity of FAM22D through cAMP-dependent pathways. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $30.00 $60.00 $93.00 | 27 | |
H2O2 serves as a signaling molecule that can modulate the activity of various protein kinases and phosphatases, potentially altering the phosphorylation state and activity of FAM22D. | ||||||
(±)-S-Nitroso-N-acetylpenicillamine | 79032-48-7 | sc-200319B sc-200319 sc-200319A | 10 mg 20 mg 100 mg | $73.00 $112.00 $367.00 | 18 | |
SNAP releases nitric oxide, which can activate guanylyl cyclase and increase cGMP levels. Elevated cGMP activates PKG, which can then influence the phosphorylation and activity of FAM22D if it is part of cGMP-dependent signaling pathways. | ||||||