The chemical class denoted as FAIM2 Activators encompasses a diverse range of compounds that exhibit the potential to influence the activity of Fas apoptotic inhibitory molecule 2 (FAIM2), a protein encoded by the FAIM2 gene. FAIM2 plays a crucial role in cellular processes, particularly in the regulation of apoptosis and immune responses. The activators within this class operate through various signaling pathways, providing distinct avenues for the modulation of FAIM2 activity. In addition, AMP-activated protein kinase (AMPK) activators have the potential to activate FAIM2 by enhancing AMPK signaling. This activation may result in downstream effects that impact FAIM2 and contribute to the modulation of cellular processes governed by FAIM2.
FAIM2 Activators elevate intracellular cyclic AMP (cAMP) levels through their action on AMPK. This represents additional activators influencing FAIM2 activity. Furthermore, activaors engage the JAK/STAT pathway, potentially activating FAIM2 and contributing to the intricate network of signaling pathways regulating this protein. They also can act through peroxisome proliferator-activated receptor-gamma (PPARγ), offering an alternative mechanism for FAIM2 modulation. Lastly, activaors induce FAIM2 through distinct pathways such as Nrf2, mitochondrial function, and protein phosphatase activity, respectively. This diverse array of FAIM2 activators reflects the complexity of cellular regulation and provides a comprehensive framework for understanding the nuanced control of FAIM2 in cellular processes. In summary, the FAIM2 Activators class showcases a myriad of compounds with the potential to modulate FAIM2 activity through various signaling pathways. The intricate interplay between these activators and the diverse regulatory mechanisms they engage highlight the complexity of FAIM2's role in cellular processes, offering valuable insights into the molecular control of apoptosis and immune responses.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
A-769662 | 844499-71-4 | sc-203790 sc-203790A sc-203790B sc-203790C sc-203790D | 10 mg 50 mg 100 mg 500 mg 1 g | $180.00 $726.00 $1055.00 $3350.00 $5200.00 | 23 | |
A769662 can potentially activate FAIM2 by influencing AMPK signaling. As an AMPK activator, it may enhance AMPK activity, leading to downstream effects that impact FAIM2 activation and cellular processes. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin can potentially activate FAIM2 by influencing cAMP levels. Its role in elevating cAMP may affect FAIM2 activity, contributing to downstream signaling cascades and cellular events. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AICAR is a potential activator of FAIM2 that acts through AMPK signaling. By activating AMPK, AICAR may influence FAIM2 activity, contributing to the modulation of cellular processes regulated by FAIM2. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $42.00 $62.00 $153.00 $255.00 $500.00 $30.00 | 37 | |
1,1-Dimethylbiguanide, Hydrochloride can potentially activate FAIM2 by modulating AMPK signaling. Its action in activating AMPK may impact FAIM2 activity, leading to downstream effects that influence cellular processes regulated by FAIM2. | ||||||
Lipase Inhibitor, THL | 96829-58-2 | sc-203108 | 50 mg | $51.00 | 7 | |
Lipase Inhibitor, THL can potentially activate FAIM2 through its role in JAK/STAT signaling. By engaging the JAK/STAT pathway, leptin may impact FAIM2 activation and contribute to the regulation of cellular processes influenced by FAIM2. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $118.00 $320.00 $622.00 $928.00 $1234.00 | 38 | |
Rosiglitazone is a potential FAIM2 activator that acts through the PPARγ pathway. By modulating PPARγ activity, rosiglitazone may influence FAIM2 expression and contribute to the regulation of cellular processes associated with FAIM2. | ||||||
Streptozotocin (U-9889) | 18883-66-4 | sc-200719 sc-200719A | 1 g 5 g | $110.00 $510.00 | 152 | |
Streptozotocin can potentially activate FAIM2 by modulating the Nrf2 pathway. Its role in activating Nrf2 may impact FAIM2 expression, contributing to the regulation of cellular processes associated with FAIM2. | ||||||
Adenosine phosphate(Vitamin B8) | 61-19-8 | sc-278678 sc-278678A | 50 g 100 g | $160.00 $240.00 | ||
Adenosine phosphate can potentially activate FAIM2 by influencing AMPK signaling. As a direct substrate of AMPK, AMP may enhance AMPK activity, leading to downstream effects that impact FAIM2 activation and cellular processes. | ||||||
Nicotinamide riboside | 1341-23-7 | sc-507345 | 10 mg | $411.00 | ||
Nicotinamide riboside is a potential FAIM2 activator that acts through the NAD+ pathway. By modulating NAD+ levels, it may influence FAIM2 activity, contributing to the regulation of cellular processes associated with FAIM2. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
2-Deoxyglucose can potentially activate FAIM2 by influencing glucose metabolism. Its impact on glucose metabolism may affect FAIM2 activity, contributing to the regulation of cellular processes associated with FAIM2. | ||||||