The term EVPLL Inhibitors refers to a specialized class of chemical compounds designed to modulate the activity of EVPLL, a molecular target currently under scientific investigation. These inhibitors are meticulously crafted through principles rooted in medicinal chemistry, with a primary focus on selectively interfering with the normal functions of EVPLL within cellular processes. The structural features of EVPLL Inhibitors undergo a rigorous optimization process, often involving computational modeling and structure-activity relationship studies, to ensure their molecular configurations are precisely tailored for effective binding to the target.
The significance of EVPLL Inhibitors lies in their potential to disrupt the biochemical activities associated with EVPLL, a molecular entity believed to play a role in various biological pathways. Researchers in this field delve into the three-dimensional structure of EVPLL and its binding interactions with inhibitors, aiming to unravel the intricate molecular mechanisms underlying inhibition. The study of EVPLL Inhibitors contributes to a broader understanding of cellular processes, offering insights into the roles played by EVPLL in diverse biological pathways and expanding our knowledge of the regulatory networks governing cellular activities. This research not only advances our comprehension of the molecular intricacies surrounding EVPLL but also contributes to the broader scientific understanding of molecular targets and their involvement in fundamental cellular functions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D intercalates into DNA, thus inhibiting RNA polymerase movement and blocking mRNA synthesis. | ||||||
Mitomycin C | 50-07-7 | sc-3514A sc-3514 sc-3514B | 2 mg 5 mg 10 mg | $65.00 $99.00 $140.00 | 85 | |
Mitomycin C forms cross-links within DNA strands, which can prevent DNA replication and transcription. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $173.00 $418.00 | 43 | |
Doxorubicin intercalates into DNA and interacts with topoisomerase II, inhibiting DNA replication and transcription. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
Etoposide stabilizes the DNA-topoisomerase II complex, preventing the ligation of DNA strands and affecting transcription. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Mithramycin binds to DNA and inhibits RNA synthesis, which could reduce the production of mRNA for the protein. | ||||||
Rocaglamide | 84573-16-0 | sc-203241 sc-203241A sc-203241B sc-203241C sc-203241D | 100 µg 1 mg 5 mg 10 mg 25 mg | $270.00 $465.00 $1607.00 $2448.00 $5239.00 | 4 | |
Rocaglamide has been reported to inhibit translation initiation, potentially reducing protein synthesis. | ||||||
Homoharringtonine | 26833-87-4 | sc-202652 sc-202652A sc-202652B | 1 mg 5 mg 10 mg | $51.00 $123.00 $178.00 | 11 | |
Homoharringtonine inhibits the initial elongation step of protein synthesis by preventing the proper elongation of nascent peptide chains. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Cycloheximide inhibits eukaryotic ribosomes, blocking the translocation step in protein synthesis. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Anisomycin interferes with the peptidyl transferase activity of the ribosome, inhibiting protein synthesis. | ||||||
Puromycin dihydrochloride | 58-58-2 | sc-108071 sc-108071B sc-108071C sc-108071A | 25 mg 250 mg 1 g 50 mg | $40.00 $210.00 $816.00 $65.00 | 394 | |
Puromycin causes premature chain termination during translation by acting as an analog of aminoacyl-tRNA. | ||||||