ERK 5 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
XMD 8-92 Trifluoroacetate | 1234480-50-2 (free base) | sc-361408 sc-361408A | 10 mg 50 mg | $230.00 $865.00 | 3 | |
XMD 8-92 Trifluoroacetate acts as a selective inhibitor of ERK 5, influencing its phosphorylation and subsequent signaling pathways. This compound exhibits unique binding interactions that disrupt the ATP-binding site of ERK 5, altering its activation kinetics. By modulating the downstream effects of ERK 5, XMD 8-92 Trifluoroacetate can impact cellular responses to stress and growth signals, highlighting its role in regulating cellular homeostasis and signaling networks. | ||||||
BIX 02189 | 1094614-85-3 | sc-364436 sc-364436A | 5 mg 10 mg | $224.00 $386.00 | 5 | |
BIX02189 is a selective small-molecule inhibitor of ERK 5 that binds to the ATP-binding pocket of the kinase. It has demonstrated anti-proliferative effects in cancer cells and shows promise as a potential therapeutic agent. | ||||||
XMD 8-92 (free base) | 1234480-50-2 | sc-364068 sc-364068A sc-364068B sc-364068C | 5 mg 10 mg 100 mg 1 g | $235.00 $340.00 $1700.00 $10330.00 | 10 | |
XMD 8-92 (free base) is a potent modulator of ERK 5 activity, characterized by its ability to selectively interfere with the enzyme's conformational dynamics. This compound engages in specific molecular interactions that stabilize inactive states of ERK 5, effectively hindering its activation. The unique kinetic profile of XMD 8-92 allows for precise regulation of downstream signaling cascades, influencing cellular responses and maintaining intricate balance within signaling networks. | ||||||
VX-11e | 896720-20-0 | sc-507301 | 10 mg | $180.00 | ||
VX-11e is a small-molecule inhibitor that selectively targets ERK It has demonstrated anti-proliferative effects in cancer cells and shows potential as a therapeutic agent in cancer research. | ||||||