Drebrin Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(±)-Blebbistatin | 674289-55-5 | sc-203532B sc-203532 sc-203532A sc-203532C sc-203532D | 5 mg 10 mg 25 mg 50 mg 100 mg | $183.00 $313.00 $464.00 $942.00 $1723.00 | 7 | |
Blebbistatin inhibits Drebrin indirectly by disrupting actin dynamics. It specifically targets non-muscle myosin II, preventing its interaction with actin filaments and influencing the cytoskeletal organization that Drebrin relies on for cellular functions. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $265.00 $815.00 | 36 | |
Latrunculin A inhibits Drebrin by disrupting actin polymerization. It sequesters monomeric actin, preventing its incorporation into growing actin filaments. This disruption of actin dynamics impacts Drebrin's ability to interact with actin and modulate cellular processes. | ||||||
CK 666 | 442633-00-3 | sc-361151 sc-361151A | 10 mg 50 mg | $321.00 $1040.00 | 5 | |
CK666 inhibits Drebrin indirectly by targeting the Arp2/3 complex, crucial for actin filament branching. By inhibiting Arp2/3, CK666 disrupts the actin cytoskeleton, affecting Drebrin's functional interactions with actin and downstream cellular processes. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Cytochalasin D inhibits Drebrin by disrupting actin polymerization. It binds to the growing ends of actin filaments, preventing further elongation. This interference with actin dynamics influences Drebrin's ability to regulate actin-dependent cellular functions. | ||||||
SMIFH2 | 340316-62-3 | sc-507273 | 5 mg | $140.00 | ||
SMIFH2 inhibits Drebrin indirectly by disrupting formin-mediated actin polymerization. It specifically targets formin proteins, crucial for actin nucleation and elongation. By inhibiting formin, SMIFH2 impacts the actin cytoskeleton, affecting Drebrin-mediated cellular processes. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $184.00 $305.00 | 59 | |
Jasplakinolide inhibits Drebrin by stabilizing actin filaments. It promotes actin polymerization and stabilizes F-actin structures, preventing dynamic interactions with Drebrin. This stabilization interferes with Drebrin's ability to modulate cellular functions dependent on actin dynamics. | ||||||
CK-869 | 388592-44-7 | sc-507274 | 5 mg | $163.00 | ||
CK869 inhibits Drebrin indirectly by targeting the Arp2/3 complex. Similar to CK666, CK869 disrupts actin filament branching, affecting the actin cytoskeleton and Drebrin-mediated cellular processes by inhibiting the essential Arp2/3 complex involved in actin dynamics. | ||||||
Latrunculin B | 76343-94-7 | sc-203318 | 1 mg | $240.00 | 29 | |
Latrunculin B inhibits Drebrin by disrupting actin polymerization, similar to Latrunculin A. It sequesters monomeric actin, preventing its incorporation into growing actin filaments. This interference with actin dynamics impacts Drebrin's ability to regulate actin-dependent cellular functions. | ||||||
Cytochalasin B | 14930-96-2 | sc-3519 | 5 mg | $199.00 | 19 | |
Cytochalasin B inhibits Drebrin by disrupting actin polymerization, similar to Cytochalasin D. It binds to the growing ends of actin filaments, preventing further elongation. This interference with actin dynamics impacts Drebrin's ability to regulate actin-dependent cellular functions. | ||||||