Date published: 2026-5-17

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DNA pol lambda Inhibitors

Santa Cruz Biotechnology now offers a broad range of DNA pol lambda Inhibitors for use in various applications. DNA polymerase lambda (pol lambda) is a key enzyme involved in the repair of DNA damage, particularly in non-homologous end joining (NHEJ), a critical pathway for repairing double-strand breaks in DNA. DNA pol lambda also plays a role in base excision repair (BER), making it essential for maintaining genomic stability. DNA pol lambda Inhibitors are crucial tools in scientific research, allowing researchers to study the enzyme's function in DNA repair processes and how its inhibition impacts cellular responses to DNA damage. By using these inhibitors, scientists can explore the consequences of impaired DNA repair, such as increased mutation rates, genomic instability, and the potential implications for cancer development and progression. These inhibitors are widely employed in studies aimed at understanding the molecular mechanisms of DNA repair, providing insights into how cells maintain the integrity of their genetic material under various conditions of stress and damage. Additionally, DNA pol lambda Inhibitors are valuable in research focusing on the interplay between different DNA repair pathways and their regulation. The availability of these inhibitors has significantly advanced research in fields such as molecular biology, genetics, and cancer biology, offering essential tools for dissecting the complex processes that ensure the accurate repair of DNA and the preservation of genomic stability. View detailed information on our available DNA pol lambda Inhibitors by clicking on the product name.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Heptelidic acid

74310-84-2sc-391051A
sc-391051
250 µg
1 mg
$194.00
$475.00
3
(1)

Heptelidic acid functions as a modulator of DNA polymerase lambda, showcasing distinctive interactions that enhance its affinity for the enzyme's active site. Its unique structural features promote specific conformational changes, influencing the enzyme's catalytic efficiency. The compound's ability to form stable complexes with DNA substrates alters reaction kinetics, while its amphiphilic nature may impact membrane interactions, potentially affecting cellular processes related to DNA repair and replication.

18 β-Glycyrrhetinic Acid

471-53-4sc-205573B
sc-205573
sc-205573A
sc-205573C
sc-205573D
1 g
5 g
10 g
25 g
100 g
$29.00
$55.00
$87.00
$132.00
$319.00
3
(2)

18 β-Glycyrrhetinic Acid exhibits intriguing properties as a modulator of DNA polymerase lambda, characterized by its ability to stabilize enzyme-DNA complexes through hydrogen bonding and hydrophobic interactions. This compound influences the enzyme's conformational dynamics, enhancing its processivity and fidelity during DNA synthesis. Additionally, its structural versatility allows for unique interactions with metal ions, potentially affecting enzymatic activity and substrate specificity in nucleic acid metabolism.