DEPDC5 Inhibitors
DEPDC5 inhibitors form a chemical class of compounds specifically designed to selectively and reversibly target DEPDC5 (DEP domain-containing protein 5), a protein crucial for regulating the mTOR (mechanistic target of rapamycin) signaling pathway. mTOR signaling plays diverse roles in cellular processes, including cell growth, proliferation, and metabolism. These inhibitors are meticulously engineered to interact with DEPDC5, aiming to disrupt its activity and modulate the mTOR signaling cascade. The chemical structure of DEPDC5 inhibitors allows them to bind to specific regions or binding sites on the protein, potentially interfering with its regulatory role in the mTOR pathway.
Researchers employ DEPDC5 inhibitors in biochemical and cellular studies to unravel the intricacies of DEPDC5's functions in mTOR signaling and its potential implications in various biological contexts. The design and development of these inhibitors rely on a comprehensive understanding of DEPDC5's structural features and its involvement in mTOR signaling, providing valuable tools for advancing research in the field of cellular signaling and regulatory mechanisms.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Thalidomide | 50-35-1 | sc-201445 sc-201445A | 100 mg 500 mg | $111.00 $357.00 | 8 | |
Thalidomide, a drug with immunomodulatory and anti-inflammatory properties, has been reported to inhibit DEPDC5 and impact mTOR signaling. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin is a well-known mTOR inhibitor that indirectly affects DEPDC5-regulated mTOR signaling. | ||||||
Everolimus | 159351-69-6 | sc-218452 sc-218452A | 5 mg 50 mg | $131.00 $651.00 | 7 | |
Everolimus is another mTOR inhibitor that indirectly modulates DEPDC5-dependent mTOR signaling. | ||||||
scyllo-Inositol | 488-59-5 | sc-202808 sc-202808A | 5 mg 25 mg | $72.00 $220.00 | ||
Certain inositol derivatives have been reported to inhibit DEPDC5 and modulate mTOR signaling. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $65.00 $280.00 $400.00 | 48 | |
AICAR is an activator of AMP-activated protein kinase (AMPK) that has been shown to modulate DEPDC5-dependent mTOR signaling. | ||||||
Uridine | 58-96-8 | sc-296685 sc-296685A | 1 g 25 g | $61.00 $100.00 | 1 | |
Uridine is a nucleoside that has been reported to modulate DEPDC5 and mTOR signaling. | ||||||
INK 128 | 1224844-38-5 | sc-364511 sc-364511A | 5 mg 50 mg | $321.00 $1835.00 | ||
INK128 is a dual inhibitor of mTOR and other PI3K-related kinases that affects DEPDC5-mediated mTOR signaling. | ||||||