Cyclosporin A Inhibitors
Cyclosporin A inhibitors belong to a distinct chemical class renowned for their ability to selectively interfere with the action of cyclosporin A. Cyclosporin A itself is a cyclic polypeptide found in a fungus and possesses potent immunosuppressive properties. The inhibitors specifically target the molecular mechanisms associated with cyclosporin A's function, which involves modulating the immune response. These inhibitors act by binding to crucial sites on the cyclosporin A molecule, thereby impeding its normal activity and leading to a reduction in its overall immunosuppressive effects.
As a result, the cyclosporin A inhibitors have the ability to serve as valuable tools for further research and understanding of cyclosporin A's intricate mode of action within the immune system. Their unique properties and selectivity make them a significant subject of interest in the scientific community, paving the way for a deeper comprehension of immunosuppressive processes.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Verapamil | 52-53-9 | sc-507373 | 1 g | $374.00 | ||
Verapamil is a calcium channel blocker that can inhibit the metabolism of cyclosporin A, leading to increased levels of cyclosporin in the bloodstream. | ||||||
Diltiazem | 42399-41-7 | sc-204726 sc-204726A | 1 g 5 g | $209.00 $464.00 | 4 | |
Like verapamil, diltiazem is a calcium channel blocker that can interfere with the metabolism of cyclosporin A. | ||||||
Ketoconazole | 65277-42-1 | sc-200496 sc-200496A | 50 mg 500 mg | $63.00 $265.00 | 21 | |
Ketoconazole (CAS 65277-42-1) functions as an inhibitor of Cyclosporin A by interfering with its metabolic pathways. It inhibits Cyclosporin A′s activity through its impact on cytochrome P450 enzymes, reducing the protein′s overall effectiveness in biological processes. This interaction makes Ketoconazole useful in research for studying the regulation of Cyclosporin A and its role in various molecular mechanisms. | ||||||
Erythromycin | 114-07-8 | sc-204742 sc-204742A sc-204742B sc-204742C | 5 g 25 g 100 g 1 kg | $57.00 $245.00 $831.00 $1331.00 | 4 | |
Erythromycin (CAS 114-07-8) acts as an inhibitor of Cyclosporin A by interfering with its metabolism, particularly through the inhibition of cytochrome P450 enzymes. This interaction decreases the activity of Cyclosporin A, allowing for the study of its molecular pathways and the regulation of its function in various biological systems. Erythromycin′s role as a Cyclosporin A inhibitor is valuable for research into protein interactions and enzymatic control mechanisms. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $97.00 $328.00 $676.00 $1467.00 | 6 | |
Rifampin can accelerate the metabolism of cyclosporin A, reducing its effectiveness. | ||||||
FK-506 | 104987-11-3 | sc-24649 sc-24649A | 5 mg 10 mg | $78.00 $151.00 | 9 | |
FK-506 (CAS 104987-11-3) inhibits Cyclosporin A by binding to immunophilins, affecting the same cellular pathways as Cyclosporin A but with a distinct mechanism. It disrupts the activity of calcineurin, leading to a reduction in Cyclosporin A′s functional capacity. This interaction is valuable for research into protein-protein interactions and the regulation of signaling pathways within biological systems. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin (CAS 53123-88-9) is a macrolide compound that functions as a potent inhibitor of Cyclosporin A protein. It exerts its inhibitory effect by forming a complex with FK506-binding protein 12 (FKBP12), which then targets and suppresses the mechanistic target of rapamycin (mTOR) pathway. This interaction results in the inhibition of cellular processes associated with Cyclosporin A activity, making Rapamycin a valuable tool in scientific research focused on protein regulation and cellular signaling pathways. | ||||||
Fluconazole | 86386-73-4 | sc-205698 sc-205698A | 500 mg 1 g | $54.00 $84.00 | 14 | |
This antifungal agent can inhibit cyclosporin A metabolism, leading to increased blood concentrations. | ||||||
Clarithromycin | 81103-11-9 | sc-205634 sc-205634A | 100 mg 250 mg | $77.00 $122.00 | 1 | |
Clarithromycin, an antibiotic, can inhibit the metabolism of cyclosporin A, increasing its levels in the body. | ||||||
Amiodarone | 1951-25-3 | sc-480089 | 5 g | $318.00 | ||
Amiodarone (CAS 1951-25-3) acts as an inhibitor of Cyclosporin A by interacting with the protein′s pathways involved in signal transduction and molecular interactions. Through its inhibition, Amiodarone disrupts Cyclosporin A′s binding capacity, affecting the regulation of its downstream effects. This makes Amiodarone a valuable tool in research focused on protein-protein interactions and intracellular signaling dynamics. | ||||||