Date published: 2025-12-8

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CTRP4 Activators

CTRP4, or C1q/TNF-Related Protein 4, is a gene that encodes a member of the C1q/TNF-related protein (CTRP) family. The CTRP family is part of the larger adipokine family, which includes proteins secreted by adipose (fat) tissue and involved in various metabolic processes.CTRP4, like other CTRPs, is characterized by its C1q domain, similar to that found in proteins of the complement system and tumor necrosis factor (TNF) superfamily. This domain is important for the protein's structure and function, particularly in its interactions with other molecules.The protein encoded by CTRP4 is involved in several physiological processes, mainly related to metabolism and energy homeostasis. It has been implicated in the regulation of glucose and lipid metabolism, suggesting a role in metabolic conditions such as obesity, diabetes, and cardiovascular diseases.

CTRP4 is expressed in various tissues, but its highest expression is typically found in adipose tissue. It functions as a circulating factor, influencing metabolic processes in different parts of the body. Research suggests that CTRP4 can impact insulin sensitivity and glucose utilization, which are crucial factors in the management of blood sugar levels and metabolic health.In addition to its metabolic roles, CTRP4 may also be involved in other physiological processes, such as inflammation and cellular stress responses. These broader functions indicate that CTRP4 could have implications in a range of health conditions beyond metabolic disorders.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Pioglitazone

111025-46-8sc-202289
sc-202289A
1 mg
5 mg
$54.00
$123.00
13
(1)

A PPAR-gamma agonist, Pioglitazone can influence metabolic pathways, potentially impacting CTRP4 activity.

Rosiglitazone

122320-73-4sc-202795
sc-202795A
sc-202795C
sc-202795D
sc-202795B
25 mg
100 mg
500 mg
1 g
5 g
$118.00
$320.00
$622.00
$928.00
$1234.00
38
(1)

Similar to Pioglitazone, Rosiglitazone is a PPAR-gamma agonist that may indirectly affect CTRP4 function in metabolic regulation.

Metformin

657-24-9sc-507370
10 mg
$77.00
2
(0)

Primarily used in diabetes management, Metformin can modulate metabolic pathways, potentially influencing CTRP4.

Fenofibrate

49562-28-9sc-204751
5 g
$40.00
9
(1)

A PPAR-alpha agonist, Fenofibrate influences lipid metabolism and could indirectly affect CTRP4.

Exendin-4

141758-74-9sc-474611
sc-474611A
500 µg
1 mg
$143.00
$194.00
1
(0)

A GLP-1 receptor agonist, Exendin-4 can influence glucose metabolism, potentially impacting CTRP4.

Liraglutide

204656-20-2sc-507404
1 mg
$220.00
(0)

Another GLP-1 receptor agonist, Liraglutide affects glucose homeostasis and might influence CTRP4.