CPVL Activators
CPVL activators encompass a spectrum of chemicals primarily centered around the provision of cofactors and stabilization of the protein's structure. Metal ions like zinc, magnesium, copper, and manganese, supplied through their respective salts, are fundamental in catalyzing reactions for metalloenzymes. They contribute either to the structural integrity or to the catalytic activity of enzymes like CPVL. Compounds such as Coenzyme A and Pyridoxal Phosphate serve as organic cofactors, facilitating enzymatic reactions by forming enzyme-cofactor complexes, which may augment the functional capacity of CPVL.
Further stabilization of CPVL can be achieved through the use of amino acids such as histidine, which can chelate metal ions within the active site, enhancing enzymatic activity. Alpha-ketoglutarate and NADH, while not direct activators, contribute to the overall metabolic environment, which is conducive to optimal enzyme function. Agents like DTT and glycerol maintain the enzyme in a reduced state and structurally stable, respectively, ensuring that CPVL remains in a configuration that is primed for activity. EDTA, although generally a chelator, can be used to fine-tune the availability of metal ions, ensuring that CPVL has the requisite ions for its activity without the interference of excess metal that could lead to inhibition.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc is a known cofactor for metalloenzymes. Zinc sulfate can provide zinc ions, which can bind to carboxypeptidases like CPVL, potentially restoring its catalytic activity if it is zinc-dependent. | ||||||
Magnesium chloride | 7786-30-3 | sc-255260C sc-255260B sc-255260 sc-255260A | 10 g 25 g 100 g 500 g | $27.00 $34.00 $47.00 $123.00 | 2 | |
Magnesium ions are essential for many enzymes as a cofactor. Magnesium chloride can supply these ions, potentially enhancing the enzymatic activity of CPVL if it requires magnesium for its structure or function. | ||||||
Coenzyme A | 85-61-0 anhydrous | sc-211123 sc-211123A sc-211123B sc-211123C | 10 mg 25 mg 100 mg 250 mg | $70.00 $116.00 $410.00 $785.00 | 1 | |
As a cofactor, Coenzyme A can facilitate the activity of various carboxypeptidases by binding to and stabilizing their active sites, potentially increasing CPVL activity. | ||||||
Pyridoxal-5-phosphate | 54-47-7 | sc-205825 | 5 g | $102.00 | ||
This is the active form of vitamin B6 and serves as a cofactor for many enzyme reactions, possibly promoting CPVL activity by stabilizing the enzyme-substrate complex. | ||||||
Copper(II) sulfate | 7758-98-7 | sc-211133 sc-211133A sc-211133B | 100 g 500 g 1 kg | $45.00 $120.00 $185.00 | 3 | |
Copper ions can act as essential cofactors for various enzymes. Copper sulfate might enhance CPVL activity if it functions as a copper-dependent carboxypeptidase. | ||||||
Manganese(II) chloride beads | 7773-01-5 | sc-252989 sc-252989A | 100 g 500 g | $19.00 $30.00 | ||
Manganese is a cofactor for several metalloproteins and might be involved in activating CPVL if it is manganese-reliant. | ||||||
L-Histidine | 71-00-1 | sc-394101 sc-394101A sc-394101B sc-394101C sc-394101D | 25 g 100 g 250 g 500 g 1 kg | $53.00 $82.00 $185.00 $200.00 $332.00 | 1 | |
As a known metalloenzyme stabilizer, histidine might improve the catalytic function of CPVL by assisting in metal ion coordination at the active site. | ||||||
α-Ketoglutaric Acid | 328-50-7 | sc-208504 sc-208504A sc-208504B sc-208504C sc-208504D sc-208504E sc-208504F | 25 g 100 g 250 g 500 g 1 kg 5 kg 16 kg | $32.00 $42.00 $62.00 $108.00 $184.00 $724.00 $2050.00 | 2 | |
This compound is involved in the Krebs cycle but also assists in the regulation of enzyme function and might support CPVL activity indirectly by providing a conducive metabolic environment. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $56.00 $186.00 $296.00 $655.00 $2550.00 $3500.00 $10500.00 | 4 | |
Nicotinamide adenine dinucleotide (NADH) supports numerous enzymatic reactions. Supplementing with NADH might indirectly enhance CPVL activity by maintaining cellular redox state. | ||||||
Glycerol | 56-81-5 | sc-29095A sc-29095 | 100 ml 1 L | $55.00 $150.00 | 12 | |
Often used as a stabilizing agent for enzymes, glycerol might maintain the structural integrity of CPVL and promote its enzymatic activity. | ||||||