CLTCL1 Inhibitors refer to a specialized class of chemical compounds designed to selectively impede the activity of the CLTCL1 protein. CLTCL1, or Clathrin Heavy Chain-like 1, is a member of the clathrin heavy chain family, known for its role in membrane trafficking and vesicle formation within cells. The development of inhibitors targeting CLTCL1 is crucial for scientific investigations, providing researchers with specific tools to delve into the molecular functions and cellular processes associated with this particular protein. As part of the clathrin heavy chain family, CLTCL1 is likely involved in the assembly of clathrin-coated vesicles, essential for intracellular transport and the maintenance of cellular membrane dynamics.
The synthesis and optimization of CLTCL1 inhibitors demand a meticulous understanding of the protein's structural characteristics and its interactions within cellular pathways. These inhibitors are designed for specificity, aiming to selectively bind to key regions of CLTCL1 and disrupt its normal cellular functions. By utilizing CLTCL1 inhibitors in experimental contexts, scientists can investigate the consequences of protein inhibition on intracellular trafficking, shedding light on the specific roles played by CLTCL1 in cellular membrane dynamics and vesicle formation. The study of CLTCL1 inhibitors contributes to the broader understanding of clathrin-mediated processes, providing insights into the intricate molecular machinery that underlies essential cellular functions, such as endocytosis and the regulation of membrane-bound organelles.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D inhibits transcription by binding to DNA, thus preventing the synthesis of CLTCL1 mRNA. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Cycloheximide disrupts protein synthesis, leading to a reduction in CLTCL1 expression by inhibiting translation. | ||||||
Puromycin dihydrochloride | 58-58-2 | sc-108071 sc-108071B sc-108071C sc-108071A | 25 mg 250 mg 1 g 50 mg | $40.00 $210.00 $816.00 $65.00 | 394 | |
Puromycin induces premature termination of protein synthesis, impacting the translation process and lowering CLTCL1 levels. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $95.00 $322.00 $663.00 $1438.00 | 6 | |
Rifampicin inhibits bacterial RNA polymerase, indirectly suppressing CLTCL1 expression by interfering with transcription. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Anisomycin hinders protein synthesis by blocking peptidyl transferase activity, resulting in reduced CLTCL1 synthesis. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $99.00 | 5 | |
Cordycepin interferes with mRNA synthesis, impacting transcription and contributing to the downregulation of CLTCL1. | ||||||
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $68.00 $261.00 | 8 | |
Mycophenolic acid inhibits inosine monophosphate dehydrogenase, indirectly affecting CLTCL1 expression by disrupting purine synthesis. | ||||||
Blasticidin S Hydrochloride | 3513-03-9 | sc-204655A sc-204655 | 25 mg 100 mg | $360.00 $475.00 | 20 | |
Blasticidin S induces premature termination during translation, inhibiting protein synthesis and reducing CLTCL1 synthesis. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $36.00 $149.00 | 11 | |
5-Fluorouracil interferes with RNA synthesis, affecting the expression of CLTCL1 by disrupting the production of mRNA. | ||||||