Ceramide Kinase Inhibitors
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Fingolimod | 162359-55-9 | sc-507334 | 10 mg | $160.00 | ||
Fingolimod is a sphingosine-1-phosphate receptor modulator, capable of disrupting the sphingolipid metabolism, thereby indirectly impacting CERK's function. | ||||||
NVP-231 | 362003-83-6 | sc-255397 | 5 mg | $115.00 | ||
NVP-231 functions as a ceramide kinase, engaging in the phosphorylation of ceramide to generate ceramide-1-phosphate. This process is crucial for regulating sphingolipid metabolism. The compound exhibits a unique affinity for the enzyme's active site, facilitating specific molecular interactions that stabilize the enzyme-substrate complex. Its kinetic behavior reveals a non-competitive inhibition pattern, allowing for nuanced control over ceramide signaling pathways and cellular responses. | ||||||
D609 | 83373-60-8 | sc-201403 sc-201403A | 5 mg 25 mg | $189.00 $575.00 | 7 | |
D609 is a phosphatidylcholine-specific phospholipase C inhibitor, which can interfere with CERK by inhibiting ceramide production. | ||||||
Myriocin (ISP-1) | 35891-70-4 | sc-201397 | 10 mg | $150.00 | 8 | |
Myriocin is a serine palmitoyltransferase inhibitor that can disrupt sphingolipid biosynthesis, indirectly inhibiting CERK. | ||||||
D-erythro-Sphingosine | 123-78-4 | sc-3546 sc-3546A sc-3546B sc-3546C sc-3546D sc-3546E | 10 mg 25 mg 100 mg 1 g 5 g 10 g | $90.00 $194.00 $510.00 $2448.00 $9384.00 $15300.00 | 2 | |
Sphingosine competes with ceramide, the substrate of CERK, leading to a decrease in CERK activity. | ||||||
GW4869 | 6823-69-4 | sc-218578 sc-218578A | 5 mg 25 mg | $203.00 $611.00 | 24 | |
GW4869 is a neutral sphingomyelinase inhibitor, affecting the production of ceramide and thus indirectly influencing CERK. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $63.00 $92.00 $250.00 $485.00 $1035.00 $2141.00 | 69 | |
Cyclosporine A inhibits calcineurin, a protein phosphatase that can regulate ceramide metabolism and indirectly modulate CERK activity. | ||||||
DL-PDMP | 73257-80-4 | sc-201391 sc-201391B sc-201391A sc-201391C | 10 mg 25 mg 50 mg 100 mg | $119.00 $273.00 $515.00 $837.00 | 3 | |
PDMP inhibits glucosylceramide synthase, which can influence the balance of ceramide, thus indirectly affecting CERK. | ||||||
Dihydro-D-erythro-Sphingosine | 764-22-7 | sc-203911 | 10 mg | $77.00 | ||
Sphinganine is a competitive inhibitor of serine palmitoyltransferase, and can interfere with ceramide synthesis, thereby indirectly affecting CERK. | ||||||
Imipramine | 50-49-7 | sc-507545 | 5 mg | $190.00 | ||
Imipramine is an acid sphingomyelinase inhibitor, which can disrupt ceramide metabolism and indirectly inhibit CERK. | ||||||