Date published: 2025-9-11

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CEACAM19 Activators

CEACAM19 Activators are a collection of chemical compounds that are known to enhance the functional activity of CEACAM19 through specific signaling pathways and biological processes. Forskolin, through its action on adenylate cyclase, increases cAMP levels and activates PKA, potentially resulting in the phosphorylation and functional enhancement of CEACAM19 within cell signaling networks. 8-Br-cAMP, being a cAMP analog, similarly activates PKA, which can further phosphorylate and enhance the activity of CEACAM19. Isoproterenol, as a β-adrenergic agonist, also raises intracellular cAMP levels, thereby activating PKA and influencing CEACAM19 activity.

CEACAM19 Activators include a diverse array of compounds that indirectly enhance the activity of CEACAM19 through various signaling pathways. Forskolin, by activating adenylate cyclase, induces an increase in intracellular cAMP, which in turn activates PKA. This kinase can phosphorylate and thus promote the functional activity of CEACAM19 in cAMP-dependent pathways. Similarly, 8-Br-cAMP, a stable cAMP analog, and Isoproterenol, through β-adrenergic receptor stimulation, lead to PKA activation and may enhance the phosphorylation state and activity of CEACAM19. Ionomycin, by increasing intracellular calcium levels, can activate calcium-dependent kinases that also have the potential to phosphorylate and enhance CEACAM19 function within calcium-signaling pathways.

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